{"id":"W4280642662","doi":"10.3389/fragi.2022.866861","title":"The FGFR4 Homolog KIN-9 Regulates Lifespan and Stress Responses in Caenorhabditis elegans","year":2022,"lang":"en","type":"article","venue":"Frontiers in Aging","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Caenorhabditis elegans; Biology; Genetics; Fight-or-flight response; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000653336,0.0002879836,0.000141521,0.0002653578,0.0002615574,0.0001608638,0.0001798465,0.0002325373,0.0007368627],"category_scores_gemma":[0.00007625729,0.0001178169,0.0001955768,0.00007120202,0.0001659418,0.0001748833,0.0002462488,0.0003034724,0.0002413563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000386892,"about_ca_system_score_gemma":0.0002346585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002361577,"about_ca_topic_score_gemma":0.003695261,"domain_scores_codex":[0.9999443,0.000004485821,0.000004353358,0.00001698787,0.00001600141,0.00001377115],"domain_scores_gemma":[0.999931,0.000006023301,0.00002413732,0.000005040505,0.00001140659,0.00002238095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005573144,0.000005120185,0.0002533786,0.00001864227,0.000002011703,0.00007643148,0.000008366691,0.00006990695,0.9985188,0.00005328938,0.00004404013,0.0008943636],"study_design_scores_gemma":[0.00003523875,0.0001801476,0.05121859,0.00002056003,0.00003125477,0.0004984271,0.0001117098,0.004010029,0.9382335,0.0001842498,0.005449703,0.00002661113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925113,0.001689202,0.0030297,0.00009643831,0.00002700431,0.00001535522,0.0006256356,0.0001831473,0.001822249],"genre_scores_gemma":[0.9936576,0.0007098479,0.00220996,0.0000466104,0.000004705616,0.0000234614,0.0004010566,0.00002594039,0.002920735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002361577,"threshold_uncertainty_score":0.004695714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005119611093982204,"score_gpt":0.2099735505570474,"score_spread":0.2048539394630652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}