{"id":"W4281397858","doi":"10.1002/aoc.6755","title":"Hyaluronic acid targeted metal organic framework based on iron (III) for delivery of platinum curcumin cytotoxic agent to triple negative breast cancer cell line","year":2022,"lang":"en","type":"article","venue":"Applied Organometallic Chemistry","topic":"Metal-Organic Frameworks: Synthesis and Applications","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Northern British Columbia","funders":"","keywords":"Chemistry; Cytotoxicity; Curcumin; Prodrug; Zeta potential; Drug delivery; Targeted drug delivery; Hyaluronic acid; Drug carrier; Drug; Platinum; Nuclear chemistry; Pharmacology; Nanoparticle; Nanotechnology; Organic chemistry; Biochemistry; In vitro; Materials science; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004961659,0.0002019543,0.0001012643,0.0001162658,0.00007027746,0.0001171135,0.0001430074,0.0001880038,0.000572855],"category_scores_gemma":[0.00005597853,0.00008915546,0.0001572766,0.0000829801,0.00008143697,0.0001256691,0.0001208437,0.0001505142,0.0001513506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001779929,"about_ca_system_score_gemma":0.0001214252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007418738,"about_ca_topic_score_gemma":0.001483301,"domain_scores_codex":[0.9999572,0.000003742249,0.000002640248,0.000009180003,0.00001520974,0.00001196629],"domain_scores_gemma":[0.9999772,0.000002352721,0.00000779994,0.000001941577,0.000004548307,0.000006226203],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002672493,0.000009833832,0.00005676536,0.00005160669,0.000005135133,0.00004747426,0.000008296664,0.0001379987,0.9975049,0.00006590475,0.00005116964,0.002034321],"study_design_scores_gemma":[0.000006078405,0.000110665,0.0008286794,0.000003326897,0.00001234478,0.0001251134,0.000007687891,0.0008279072,0.9954136,0.00001219532,0.002647967,0.000004531234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868482,0.003505291,0.006702648,0.00007609475,0.00004483857,0.00003998177,0.0001720458,0.0001491664,0.002461797],"genre_scores_gemma":[0.9927846,0.00100694,0.003707029,0.00004442497,0.000007119413,0.00002076814,0.000106166,0.00001199278,0.002310966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007418738,"threshold_uncertainty_score":0.001916409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01049071868132356,"score_gpt":0.2251865563558171,"score_spread":0.2146958376744935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}