{"id":"W4281401473","doi":"10.1002/cbf.3710","title":"One‐step purification and regulation of fructose 1,6‐bisphosphatase from the liver of the freeze‐tolerant wood frog, <i>Rana sylvatica</i>","year":2022,"lang":"en","type":"article","venue":"Cell Biochemistry and Function","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Fructose 1,6-bisphosphatase; Gluconeogenesis; Fructose; Glycogen; Biology; Biochemistry; Allosteric regulation; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001089567,0.0002873512,0.0001584861,0.0001709235,0.0001293797,0.000199118,0.0001610926,0.0001235072,0.0003724679],"category_scores_gemma":[0.0001088955,0.00009724923,0.0002009041,0.0001257122,0.0002296442,0.000161752,0.000134155,0.000251389,0.0001775129],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001831108,"about_ca_system_score_gemma":0.0001614796,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001193062,"about_ca_topic_score_gemma":0.002015294,"domain_scores_codex":[0.9999309,0.0000116664,0.000006531426,0.00001850063,0.00001667409,0.00001572844],"domain_scores_gemma":[0.9999242,0.00001510168,0.00002717369,0.000009626482,0.000009347069,0.00001461806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005080258,0.00001003633,0.0003056672,0.00001339573,0.000002178804,0.00002538953,0.00001380205,0.00002290505,0.9990023,0.00003679689,0.00000969831,0.0005070971],"study_design_scores_gemma":[0.00001406731,0.000245783,0.05485473,0.000006348995,0.00002262549,0.0005684286,0.0000642265,0.0006875793,0.9418949,0.00006807967,0.001564045,0.000009063319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996685,0.000728699,0.001780542,0.0000625284,0.00001003718,0.0000156661,0.0002293065,0.00002001864,0.0004682317],"genre_scores_gemma":[0.9910271,0.001013238,0.003476686,0.00005280645,0.00001506396,0.00002727708,0.002355575,0.00002171573,0.002010504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001193062,"threshold_uncertainty_score":0.002372205,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006223582433752504,"score_gpt":0.1738928515914881,"score_spread":0.1676692691577356,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}