{"id":"W4281485093","doi":"10.1186/s13041-022-00934-7","title":"Postmortem gene expression profiles in the habenulae of suicides: implication of endothelial dysfunction in the neurovascular system","year":2022,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministry of Science and ICT, South Korea; National Research Foundation of Korea; Korea University; National Research Foundation; McGill University","keywords":"Monoaminergic; Transcriptome; Biology; Depression (economics); Forebrain; Neuroscience; Gene; Bioinformatics; Medicine; Gene expression; Genetics; Central nervous system; Serotonin; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001055678,0.000154848,0.0002005893,0.0001946244,0.0001046615,0.00002457601,0.0009111534,0.00003860617,0.00001875693],"category_scores_gemma":[0.0001591962,0.0001111066,0.0001354651,0.0008003029,0.0000924702,0.0001015906,0.00009228722,0.0003231446,0.000002997209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005261794,"about_ca_system_score_gemma":0.00004440572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001166762,"about_ca_topic_score_gemma":0.000004243612,"domain_scores_codex":[0.99586,0.002113549,0.000500568,0.0004239229,0.0008689018,0.0002330028],"domain_scores_gemma":[0.9987217,0.0002321477,0.0002317344,0.0007707495,0.00002417843,0.00001949939],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003664691,0.0001724483,0.002710839,0.00004756026,9.570759e-7,0.0000861981,0.001114706,0.0007268516,0.9940893,0.0005783218,0.000025898,0.0004102608],"study_design_scores_gemma":[0.000559336,0.0001575411,0.01224391,0.00002765613,0.00001066165,0.0001265417,0.0007505183,0.000130094,0.9857385,0.00004770525,0.0001130745,0.00009451007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971516,0.00004039689,0.0004182118,0.0007092039,0.0001062121,0.001431639,0.00005933376,0.00002280538,0.00006061488],"genre_scores_gemma":[0.9984001,0.000002279608,0.00005519304,0.0008890774,0.00001268143,0.0006026021,0.00000862487,0.00002481746,0.00000462668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00953307,"threshold_uncertainty_score":0.4530794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01888435552089434,"score_gpt":0.2590354344175585,"score_spread":0.2401510788966641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}