{"id":"W4281486289","doi":"10.1002/hon.3033","title":"Exome sequencing identifies <i>PD‐L2</i> as a potential predisposition gene for lymphoma","year":2022,"lang":"en","type":"letter","venue":"Hematological Oncology","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"American Cancer Society","keywords":"Exome sequencing; Lymphoma; Cancer research; Germline; Biology; Follicular lymphoma; Gene; Genetics; Medicine; Immunology; Mutation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002669188,0.000587664,0.001793814,0.0002321855,0.0003641009,0.00005460814,0.0002763174,0.001763668,0.002250436],"category_scores_gemma":[0.0002094662,0.0004616945,0.0008217932,0.0001801138,0.0002267479,0.00007359059,0.0002716658,0.0006241979,0.0002258317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002609458,"about_ca_system_score_gemma":0.0009517788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008403266,"about_ca_topic_score_gemma":0.000004951521,"domain_scores_codex":[0.9962733,0.0002838336,0.0008592088,0.001106833,0.0006072592,0.0008695277],"domain_scores_gemma":[0.9978734,0.0007416551,0.000477993,0.0005460347,0.0001697092,0.0001912242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001075707,0.001087233,0.0001977021,0.0006483815,0.0007357879,0.06315497,0.0001062685,0.000005373631,0.001063433,0.0005686701,0.9287173,0.002639201],"study_design_scores_gemma":[0.007255333,0.006059555,0.0004952187,0.0001291109,0.00185377,0.03781375,0.0001257287,0.00007252977,0.004105552,0.00297631,0.9385507,0.0005625166],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.2223744,0.004212302,0.0003970942,0.7544308,0.003858005,0.005371807,0.0006593631,0.0006236114,0.008072655],"genre_scores_gemma":[0.1449502,0.0006249761,0.003135865,0.8258564,0.004378713,0.007497192,0.008328556,0.0001547739,0.005073321],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.07742423,"threshold_uncertainty_score":0.9997835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03654834941416964,"score_gpt":0.3103958639145961,"score_spread":0.2738475145004265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}