{"id":"W4281553725","doi":"10.1016/j.bioactmat.2022.05.018","title":"Cellulose-based composite scaffolds for bone tissue engineering and localized drug delivery","year":2022,"lang":"en","type":"review","venue":"Bioactive Materials","topic":"Advanced Cellulose Research Studies","field":"Materials Science","cited_by":307,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cellulose; Biocompatibility; Materials science; Tissue engineering; Drug delivery; Regeneration (biology); Bacterial cellulose; Biomedical engineering; Biodegradation; Bone tissue; Composite number; Nanotechnology; Chemistry; Composite material; Organic chemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000350724,0.001038194,0.0009165866,0.003475426,0.0002530364,0.0007469975,0.0004876567,0.0007280438,0.003024601],"category_scores_gemma":[0.0002378078,0.0002840233,0.0004699003,0.002878225,0.0002774638,0.0009766095,0.0004660946,0.0009860843,0.002094686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005315679,"about_ca_system_score_gemma":0.0005936886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006518162,"about_ca_topic_score_gemma":0.001356312,"domain_scores_codex":[0.9998386,0.00001829476,0.00001601837,0.00002876869,0.0000815306,0.00001685952],"domain_scores_gemma":[0.9999295,0.00002724021,0.00001525928,0.000003319416,0.00001625356,0.000008441809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005441728,0.000141179,0.0001338353,0.01870864,0.00009911138,0.0003336853,0.00007384442,0.0005653307,0.03236027,0.006307126,0.01207657,0.929146],"study_design_scores_gemma":[0.00001683826,0.0001450402,0.0009568118,0.002266521,0.00009050834,0.001561202,0.00004603492,0.0001777536,0.01067147,0.001180338,0.9828553,0.00003218347],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005309718,0.9958477,0.0005035083,0.0000771402,0.0001629632,0.00001565176,0.00002834503,0.0000130142,0.002820669],"genre_scores_gemma":[0.002344854,0.9946542,0.0007965913,0.00009384936,0.00007899895,0.00002236195,0.00005266129,0.000003079122,0.001953466],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003475426,"threshold_uncertainty_score":0.01011831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04389067079500733,"score_gpt":0.3208508084092561,"score_spread":0.2769601376142488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}