{"id":"W4281557379","doi":"10.1016/j.ijrobp.2022.05.021","title":"Combination Transarterial Chemoembolization and Stereotactic Body Radiation Therapy for Unresectable Single Large Hepatocellular Carcinoma: Results From a Prospective Phase 2 Trial","year":2022,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Population and Public Health","funders":"National Cancer Institute; Cancer Research UK","keywords":"Medicine; Hepatocellular carcinoma; Response Evaluation Criteria in Solid Tumors; Clinical endpoint; Liver cancer; Phases of clinical research; Liver transplantation; Radiosurgery; Internal medicine; Radiology; Oncology; Radiation therapy; Clinical trial; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001685566,0.001887131,0.002617869,0.0005464457,0.0003807329,0.001143044,0.0007823209,0.001043337,0.002654953],"category_scores_gemma":[0.0009758324,0.0005517137,0.001967074,0.0008436582,0.001190797,0.001103231,0.0004616798,0.002717111,0.0007326758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001048647,"about_ca_system_score_gemma":0.001107575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001239515,"about_ca_topic_score_gemma":0.002442141,"domain_scores_codex":[0.9993875,0.000281614,0.00003009027,0.0001285519,0.00006140136,0.0001108057],"domain_scores_gemma":[0.9992823,0.0001426808,0.0001780312,0.00008716923,0.00003465118,0.0002751302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8733902,0.02336183,0.008911905,0.0005994687,0.004483357,0.0001193279,0.0001647283,0.002400293,0.01185022,0.0001813697,0.002006287,0.07253097],"study_design_scores_gemma":[0.6931515,0.2785025,0.01985742,0.00004196844,0.002387938,0.0002341861,0.0000818274,0.0012491,0.002368453,0.0002893799,0.001789865,0.00004593802],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935868,0.003326285,0.0004492035,0.0003944473,0.0001448316,0.0005567531,0.0004600809,0.00006744758,0.001014171],"genre_scores_gemma":[0.9914184,0.002986035,0.0009882908,0.0005701095,0.0001953007,0.0009819062,0.001500672,0.00003977833,0.00131956],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002654953,"threshold_uncertainty_score":0.008914173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04523283540344385,"score_gpt":0.3176330521141946,"score_spread":0.2724002167107508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}