{"id":"W4281567505","doi":"10.3389/fcell.2022.903657","title":"The Roles of RANK/RANKL/OPG in Cardiac, Skeletal, and Smooth Muscles in Health and Disease","year":2022,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"RANKL; Skeletal muscle; Crosstalk; Homeostasis; Biology; Medicine; Neuroscience; Endocrinology; Internal medicine; Bioinformatics; Receptor; Activator (genetics)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004000747,0.0006700081,0.0008901826,0.002166563,0.0002962719,0.0008980232,0.0005572105,0.0008420103,0.002890562],"category_scores_gemma":[0.0004558459,0.0001889637,0.000378778,0.001939148,0.00045216,0.0009716405,0.0006728496,0.001595162,0.001588404],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005642984,"about_ca_system_score_gemma":0.001041803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009142303,"about_ca_topic_score_gemma":0.001774456,"domain_scores_codex":[0.9998591,0.00002282308,0.00002009605,0.00002169572,0.00005708707,0.00001913328],"domain_scores_gemma":[0.9998331,0.00007001092,0.00002058651,0.000005019214,0.00004983155,0.00002142196],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008637972,0.0000516286,0.0002033383,0.01342807,0.00006839332,0.0002646581,0.00008405338,0.0003468665,0.002749515,0.005615609,0.03557755,0.9415239],"study_design_scores_gemma":[0.00001275222,0.00007212176,0.0009076349,0.002588307,0.00007122776,0.001542271,0.00006211938,0.00008083358,0.0005410076,0.002600402,0.9915052,0.00001604742],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001083824,0.9983869,0.00009266993,0.0002675657,0.0001857159,0.000002409114,0.0000156687,0.000007162168,0.0009336113],"genre_scores_gemma":[0.0007373269,0.9982097,0.0001243098,0.0001408265,0.0001807055,0.000003561672,0.00002627401,0.000001199548,0.0005760238],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002890562,"threshold_uncertainty_score":0.0096699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01116663882833792,"score_gpt":0.2537027741646182,"score_spread":0.2425361353362803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}