{"id":"W4281567505","doi":"10.3389/fcell.2022.903657","title":"The Roles of RANK/RANKL/OPG in Cardiac, Skeletal, and Smooth Muscles in Health and Disease","year":2022,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"RANKL; Skeletal muscle; Crosstalk; Homeostasis; Biology; Medicine; Neuroscience; Endocrinology; Internal medicine; Bioinformatics; Receptor; Activator (genetics)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004291518,0.0002662324,0.0008891772,0.00016338,0.00008317921,0.00001341931,0.0001397039,0.0001696046,0.000004469366],"category_scores_gemma":[0.00008668163,0.0001986061,0.00008392857,0.0001332316,0.0003253455,0.000004073708,0.0003346807,0.0001718773,1.728934e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002860818,"about_ca_system_score_gemma":0.0005360601,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007958226,"about_ca_topic_score_gemma":0.000113096,"domain_scores_codex":[0.9982072,0.0004309843,0.0005160129,0.000489605,0.00006288206,0.0002933835],"domain_scores_gemma":[0.9994724,0.00006164471,0.0001526072,0.0001399406,0.000006065748,0.00016735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001197289,0.00007557353,0.02794968,0.002813692,0.00004370118,0.000007276296,0.0001543877,1.722003e-7,0.00002562809,0.00003202007,0.001718912,0.9670593],"study_design_scores_gemma":[0.0005799289,0.00006336794,0.002874541,0.0002416649,0.0000284413,0.000002705666,0.0007154898,0.000001210965,0.000006631685,0.0002234476,0.9950218,0.0002408172],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01489788,0.9840675,0.000005482867,0.00003169445,0.0002341074,0.0004401731,0.00017761,0.000002301647,0.0001432567],"genre_scores_gemma":[0.003438629,0.9954112,0.000362543,0.00009261348,0.00002371868,0.0001102867,0.000482936,0.00001653992,0.00006150443],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9933028,"threshold_uncertainty_score":0.8098922,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01116663882833792,"score_gpt":0.2537027741646182,"score_spread":0.2425361353362803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}