{"id":"W4281570801","doi":"10.1111/ijlh.13877","title":"Validation of a single tube 3‐colour immature red blood cell screening assay for the detection and enumeration of small, medium and large paroxysmal nocturnal haemoglobinuria clones by flow cytometry","year":2022,"lang":"en","type":"article","venue":"International Journal of Laboratory Hematology","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Flow cytometry; Coefficient of variation; clone (Java method); Cytometry; Correlation coefficient; Enumeration; Immunology; Biology; Medicine; Pathology; Molecular biology; Chemistry; Genetics; Chromatography; Mathematics; Statistics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009893316,0.0001215638,0.0003244195,0.0002275884,0.0001724431,0.00001730133,0.0002538687,0.0001078817,0.0001362041],"category_scores_gemma":[0.0003183209,0.0001013627,0.00007848495,0.0001297808,0.00009592505,0.0001260771,0.0001217516,0.0002300553,2.405157e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003698404,"about_ca_system_score_gemma":0.00009861105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006869207,"about_ca_topic_score_gemma":0.00001157445,"domain_scores_codex":[0.9984176,0.0004743171,0.0006814816,0.0001438086,0.0001432746,0.0001394929],"domain_scores_gemma":[0.9974577,0.0006579901,0.001072739,0.00009382439,0.0006944323,0.00002326435],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001414289,0.0003207429,0.01832774,0.00007045283,0.0007124699,0.00001016335,0.0003826543,0.00008318167,0.9769275,0.0001410333,0.001132694,0.0004771232],"study_design_scores_gemma":[0.004841117,0.0007748432,0.0051905,0.00006494902,0.0003320209,0.001219199,0.001478858,0.0002321002,0.9779262,0.000155483,0.007650406,0.000134329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9750412,0.008842114,0.0131108,0.0007352415,0.001304119,0.0002493108,0.0007054895,0.000007492328,0.000004243954],"genre_scores_gemma":[0.9991083,0.00003970358,0.0005895122,0.00007596988,0.00006723134,0.00002397546,0.00006979571,0.00001143852,0.00001414121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02406704,"threshold_uncertainty_score":0.4133451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01059511816958884,"score_gpt":0.2455443490608951,"score_spread":0.2349492308913063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}