{"id":"W4281611840","doi":"10.3233/jnd-220811","title":"Long-Term Functional Efficacy and Safety of Viltolarsen in Patients with Duchenne Muscular Dystrophy","year":2022,"lang":"en","type":"article","venue":"Journal of Neuromuscular Diseases","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute on Disability, Independent Living, and Rehabilitation Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Parent Project Muscular Dystrophy; U.S. Department of Defense","keywords":"Duchenne muscular dystrophy; Medicine; Muscular dystrophy; Term (time); Pediatrics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008740667,0.0001225348,0.0002124632,0.00009798543,0.00008029627,0.000006086846,0.0001333371,0.00003337218,0.00005160171],"category_scores_gemma":[0.00007231833,0.0001041448,0.0001287477,0.0001064484,0.00009589214,0.00001109672,0.0001189308,0.0001465541,1.974781e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001089603,"about_ca_system_score_gemma":0.00008371052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000189033,"about_ca_topic_score_gemma":0.000001452878,"domain_scores_codex":[0.9989551,0.0001772907,0.0002837873,0.000189759,0.0002584596,0.0001356421],"domain_scores_gemma":[0.9993731,0.00002072084,0.0002299356,0.0001823951,0.0001011383,0.00009274912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008830429,0.001508913,0.9580227,0.00006632748,0.0002542485,0.00005797291,0.00002249943,0.004601645,0.02533266,0.00001745411,0.0001110463,0.001174125],"study_design_scores_gemma":[0.004516632,0.001733867,0.9929764,0.00001536264,0.00008942896,0.00001789565,0.00001838734,0.000003749782,0.0001889682,0.0000190559,0.0003138394,0.000106455],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984078,0.001192621,0.00007204615,0.00004357615,0.00009514862,0.0001384554,0.00003936576,0.000001875471,0.000009091682],"genre_scores_gemma":[0.9996164,0.00009611627,0.00002564474,0.0001011369,0.00004986936,0.000004749866,0.00008602866,0.00001484523,0.000005241604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03495368,"threshold_uncertainty_score":0.4246903,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004187272440436455,"score_gpt":0.1952254893144385,"score_spread":0.1910382168740021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}