{"id":"W4281611840","doi":"10.3233/jnd-220811","title":"Long-Term Functional Efficacy and Safety of Viltolarsen in Patients with Duchenne Muscular Dystrophy","year":2022,"lang":"en","type":"article","venue":"Journal of Neuromuscular Diseases","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute on Disability, Independent Living, and Rehabilitation Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Parent Project Muscular Dystrophy; U.S. Department of Defense","keywords":"Duchenne muscular dystrophy; Medicine; Muscular dystrophy; Term (time); Pediatrics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001122298,0.0003022368,0.0009461634,0.0001517768,0.0002480919,0.0003789763,0.0002911968,0.000540718,0.001378588],"category_scores_gemma":[0.00105353,0.0001205503,0.0006704112,0.000134773,0.0003031942,0.0003441454,0.0002022277,0.0008416706,0.0001872887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004471575,"about_ca_system_score_gemma":0.0004537526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004284765,"about_ca_topic_score_gemma":0.00113154,"domain_scores_codex":[0.9995342,0.0002081286,0.00005585733,0.00007055064,0.00005946821,0.00007169514],"domain_scores_gemma":[0.9992148,0.0001797151,0.0002664506,0.00003832827,0.00006034227,0.0002402711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6735119,0.02754274,0.06662666,0.001186888,0.002022368,0.0003986118,0.0004400894,0.001240261,0.02571334,0.0001147031,0.00126892,0.1999334],"study_design_scores_gemma":[0.09101665,0.774267,0.1265871,0.0001471022,0.0009755197,0.0005058271,0.0002453019,0.0007120133,0.003940806,0.00007889071,0.001493553,0.00003028957],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976243,0.001760818,0.0000498314,0.00005073289,0.00001667789,0.00007306581,0.00009366315,0.000006417499,0.0003244647],"genre_scores_gemma":[0.9989046,0.0003702627,0.0001068173,0.0000841437,0.00002419208,0.0001041859,0.0001532893,0.000001192153,0.000251316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001378588,"threshold_uncertainty_score":0.005935311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004187272440436455,"score_gpt":0.1952254893144385,"score_spread":0.1910382168740021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}