{"id":"W4281616881","doi":"10.1093/neuonc/noac079.203","title":"GCT-09. Transcriptome and methylome profiles of CNS germ cell tumors and their comparison with testicular counterpart","year":2022,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Thompson Rivers University","funders":"","keywords":"Transcriptome; Biology; Germinoma; Seminoma; Germ cell tumors; Germ cell; Atypical teratoid rhabdoid tumor; Methylation; DNA methylation; Pathology; Immunohistochemistry; Gene expression; Genetics; Immunology; Gene; Medicine; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001271607,0.0001752486,0.0003147454,0.0005503776,0.0002809694,0.0003954364,0.0001606539,0.0002323627,0.002229714],"category_scores_gemma":[0.0002487105,0.00009556844,0.0002403494,0.0007153664,0.0001602491,0.0001255297,0.0002795423,0.0002474647,0.0004104643],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002394687,"about_ca_system_score_gemma":0.0002495721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001933963,"about_ca_topic_score_gemma":0.003002754,"domain_scores_codex":[0.9998353,0.00001391871,0.00001002019,0.00006351413,0.00004196606,0.00003528296],"domain_scores_gemma":[0.9998595,0.00001374584,0.00004686451,0.00001444511,0.00002874516,0.00003674886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002542482,0.0001082858,0.4843793,0.0004247809,0.0003436578,0.001400297,0.0006331347,0.000496793,0.4614916,0.0002170748,0.001527792,0.04643472],"study_design_scores_gemma":[0.00003005555,0.0004251388,0.9489733,0.00003295559,0.0002549589,0.006032268,0.000552626,0.00107136,0.03603928,0.0002484043,0.006321853,0.00001773629],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926203,0.001517744,0.0006927435,0.00004342768,0.00001394446,0.0000230994,0.00388177,0.00006247369,0.001144335],"genre_scores_gemma":[0.9891651,0.0006656204,0.001233511,0.00005341649,0.000009983811,0.00005616614,0.007471218,0.00003393665,0.001311053],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002229714,"threshold_uncertainty_score":0.007459164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01876538210817157,"score_gpt":0.2736661221622107,"score_spread":0.2549007400540391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}