{"id":"W4281620392","doi":"10.1186/s12915-022-01322-2","title":"Enhancer-promoter interaction maps provide insights into skeletal muscle-related traits in pig genome","year":2022,"lang":"en","type":"article","venue":"BMC Biology","topic":"Genetic Mapping and Diversity in Plants and Animals","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Agriculture","funders":"National Outstanding Youth Foundation of China; National Natural Science Foundation of China; National Youth Science Foundation","keywords":"Biology; Chromatin; ChIA-PET; Genome-wide association study; Genetics; Gene; CTCF; Enhancer; Computational biology; Chromosome conformation capture; Genome; Phenotype; Regulation of gene expression; Chromatin remodeling; Gene expression; Single-nucleotide polymorphism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002528968,0.0003491407,0.0003784125,0.00167288,0.0002389077,0.0003467228,0.0002643082,0.0003189307,0.004905454],"category_scores_gemma":[0.0005015884,0.0002447162,0.0007478523,0.001295006,0.0001701274,0.0002130335,0.0005310559,0.0004746165,0.0009076634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001977953,"about_ca_system_score_gemma":0.0002528584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001371267,"about_ca_topic_score_gemma":0.003382071,"domain_scores_codex":[0.9998176,0.00001767235,0.000008064213,0.00009997411,0.00002921156,0.00002753486],"domain_scores_gemma":[0.9995881,0.0001929227,0.0000983645,0.00003975548,0.00004007355,0.0000408633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006975812,0.0001250962,0.1630319,0.0009955374,0.0006403206,0.0006406131,0.0003299144,0.00601535,0.7698705,0.002528721,0.001913804,0.0532106],"study_design_scores_gemma":[0.00006612652,0.0002008433,0.9054274,0.00007516721,0.0006673748,0.0009728877,0.0001631111,0.02643284,0.04216047,0.005250401,0.01853998,0.00004355662],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9033785,0.003341252,0.0579419,0.0002065228,0.00004184393,0.0000583394,0.02730353,0.001423273,0.006304841],"genre_scores_gemma":[0.941217,0.0006617827,0.03452502,0.0002236301,0.00004681864,0.00009163577,0.02081301,0.0002676816,0.002153367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004905454,"threshold_uncertainty_score":0.01641041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01301354951278316,"score_gpt":0.2356727498756869,"score_spread":0.2226592003629038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}