{"id":"W4281620493","doi":"10.1101/2022.06.02.494549","title":"Stable and ancient endocytic structures navigate the complex pellicle of apicomplexan parasites","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Cambridge Institute for Medical Research, University of Cambridge; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Deutsche Forschungsgemeinschaft; Leverhulme Trust; Isaac Newton Trust; Wellcome Trust","keywords":"Endocytic cycle; Endocytosis; Biology; Apicomplexa; Cell biology; Plasmodium (life cycle); Lineage (genetic); Receptor; Plasmodium falciparum; Genetics; Parasite hosting; Immunology; Gene; Malaria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000124334,0.0001246743,0.0001228697,0.0002346901,0.0002006742,0.0005299609,0.0001229629,0.0002401911,0.001063827],"category_scores_gemma":[0.0001585464,0.0000855087,0.0001124797,0.0001618036,0.0002507334,0.0002839221,0.0003001865,0.0003288162,0.0004982896],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003394205,"about_ca_system_score_gemma":0.0001460292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006358269,"about_ca_topic_score_gemma":0.0006749073,"domain_scores_codex":[0.9999353,0.000007833052,0.000004388232,0.00001883052,0.00002030083,0.00001343365],"domain_scores_gemma":[0.9999186,0.00000972648,0.00001860751,0.00001625084,0.00002062858,0.00001622632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007588882,0.000006428037,0.003118388,0.00003666816,0.000007964522,0.0001289607,0.0000391992,0.00008371857,0.9930058,0.0009643738,0.0001540218,0.002378674],"study_design_scores_gemma":[0.00003030065,0.0001222552,0.1241859,0.00002892229,0.00003737145,0.002220617,0.0004199451,0.00467367,0.8457459,0.002127199,0.02038825,0.00001968496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911296,0.00160794,0.004547414,0.0002179396,0.00002847242,0.00001044609,0.0003621441,0.00005745804,0.002038552],"genre_scores_gemma":[0.9923478,0.0005543598,0.003173667,0.00006642449,0.00001333081,0.000008892144,0.0007394457,0.00002792835,0.003068083],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001063827,"threshold_uncertainty_score":0.003558874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0271547694700997,"score_gpt":0.2595573836628862,"score_spread":0.2324026141927865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}