{"id":"W4281621781","doi":"10.1093/sleep/zsac079.193","title":"0195 Integrated actigraphy-based biomarker for the risk of Alzheimer’s dementia","year":2022,"lang":"en","type":"article","venue":"SLEEP","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Actigraphy; Dementia; Circadian rhythm; Hazard ratio; Biomarker; Psychology; Medicine; Audiology; Physical medicine and rehabilitation; Disease; Internal medicine; Confidence interval; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001170561,0.0006371575,0.0006470106,0.001134396,0.0001917777,0.000909214,0.0005230605,0.0004303751,0.003252366],"category_scores_gemma":[0.002281427,0.0001795785,0.0006356394,0.001327682,0.0001815056,0.0003409256,0.0005043263,0.0004606496,0.0006847894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000286031,"about_ca_system_score_gemma":0.0003245284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004450296,"about_ca_topic_score_gemma":0.004256456,"domain_scores_codex":[0.9993537,0.0001793858,0.00006704161,0.0002243277,0.0001181518,0.0000572747],"domain_scores_gemma":[0.9984798,0.0003073287,0.0007044473,0.0001345658,0.0002274907,0.000146464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003389012,0.00006617419,0.982444,0.00005170636,0.0006328186,0.00004609507,0.00003107862,0.001100862,0.001427418,0.00007810191,0.0006241854,0.01315863],"study_design_scores_gemma":[0.00002415365,0.0002346006,0.9888719,0.00001923591,0.0002444071,0.0003191252,0.00003372993,0.008158771,0.000757049,0.0002944412,0.001027848,0.00001482313],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818947,0.0008370171,0.006972422,0.0001230691,0.000033009,0.00004582147,0.008478981,0.0001882667,0.001426783],"genre_scores_gemma":[0.9891322,0.0001457476,0.005986847,0.00005686796,0.00003005629,0.00007859964,0.003639317,0.00001398069,0.0009164467],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004450296,"threshold_uncertainty_score":0.01088023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03439223679253583,"score_gpt":0.3188240656130327,"score_spread":0.2844318288204968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}