{"id":"W4281634293","doi":"10.3390/cells11111816","title":"LSD1 Inhibition Enhances the Immunogenicity of Mesenchymal Stromal Cells by Eliciting a dsRNA Stress Response","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society; Cancer Research Society","keywords":"Mesenchymal stem cell; Immunogenicity; Immune system; Biology; Cancer research; Stromal cell; T cell; Context (archaeology); Immunology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001048612,0.000282051,0.0002061053,0.0001451252,0.00007728115,0.0001694791,0.00009721594,0.0001639822,0.0013976],"category_scores_gemma":[0.0000574102,0.00005427658,0.0001681223,0.00006760649,0.0001412126,0.0001076882,0.0001311085,0.0003912212,0.0003098705],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001206849,"about_ca_system_score_gemma":0.0001569548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001989895,"about_ca_topic_score_gemma":0.0002835485,"domain_scores_codex":[0.9999052,0.00002262695,0.000009170652,0.00001291041,0.00002031109,0.00002977282],"domain_scores_gemma":[0.9999328,0.00001234718,0.00001852507,0.000006579778,0.00000727838,0.00002251455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001694049,0.0000433306,0.0001018227,0.00004081083,0.000003643546,0.00002167378,0.000006683464,0.00006314716,0.997996,0.00005070007,0.00004170081,0.001461049],"study_design_scores_gemma":[0.00001186458,0.0003708318,0.0008924241,0.00000217158,0.000006622834,0.00005077223,0.000009650385,0.000379143,0.9973226,0.00001355767,0.0009388902,0.000001366371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946685,0.001188403,0.001807887,0.00009807204,0.00004105943,0.00002883081,0.0002004143,0.0000848444,0.001882016],"genre_scores_gemma":[0.9974414,0.0004700379,0.0006889768,0.00003998402,0.00001075022,0.00001935848,0.0001778364,0.000008580095,0.001143087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0013976,"threshold_uncertainty_score":0.004675448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005260936639161331,"score_gpt":0.2355338605623132,"score_spread":0.2302729239231519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}