{"id":"W4281653151","doi":"10.3390/genes13061014","title":"Secreted Protein Acidic and Rich in Cysteine as an Exercise-Induced Gene: Towards Novel Molecular Therapies for Immobilization-Related Muscle Atrophy in Elderly Patients","year":2022,"lang":"en","type":"article","venue":"Genes","topic":"Muscle metabolism and nutrition","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Atrophy; Sarcopenia; Muscle atrophy; Context (archaeology); Cysteine; Phenotype; Genetic enhancement; Gene; Medicine; Endocrinology; Bioinformatics; Chemistry; Biology; Internal medicine; Cell biology; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002790802,0.0002411226,0.0003817889,0.000269512,0.0001190975,0.0004146967,0.0002456188,0.0003614496,0.00137009],"category_scores_gemma":[0.0001104442,0.00007001925,0.000322873,0.0001867306,0.0002673806,0.0002163849,0.0001879746,0.0006180966,0.0003596591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001306788,"about_ca_system_score_gemma":0.0001990273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001430132,"about_ca_topic_score_gemma":0.0003543742,"domain_scores_codex":[0.9999315,0.00001210812,0.000008874149,0.00001503036,0.00002120883,0.00001140499],"domain_scores_gemma":[0.9999435,0.0000111267,0.00001952494,0.00000436711,0.00001324358,0.000008279814],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007804944,0.0004006059,0.001087907,0.001378627,0.00007030916,0.0004902028,0.0001307207,0.0002849499,0.8897691,0.00196417,0.001255246,0.1023877],"study_design_scores_gemma":[0.0005306269,0.008675763,0.01121041,0.0005081834,0.0007190886,0.004121842,0.0002722424,0.0014733,0.7880224,0.001329126,0.1830828,0.00005410004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7075215,0.2515867,0.02167892,0.004706407,0.001675731,0.0003070551,0.0004930074,0.0002734502,0.01175714],"genre_scores_gemma":[0.7407729,0.2152487,0.02364931,0.001561726,0.0008629458,0.0002277662,0.0006402993,0.00007089174,0.01696544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00137009,"threshold_uncertainty_score":0.004583478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008720240154297483,"score_gpt":0.2352117212775036,"score_spread":0.2264914811232061,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}