{"id":"W4281655938","doi":"10.1111/apha.13845","title":"Dining on the dead in the deep: Active <scp>NH<sub>4</sub><sup>+</sup></scp> excretion via <scp>Na<sup>+</sup>/H<sup>+</sup>(NH<sub>4</sub><sup>+</sup>)</scp> exchange in the highly ammonia tolerant Pacific hagfish, <i>Eptatretus stoutii</i>","year":2022,"lang":"en","type":"article","venue":"Acta Physiologica","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Wilfrid Laurier University; Bamfield Marine Sciences Centre; University of Alberta","funders":"National Science Foundation of Sri Lanka; Natural Sciences and Engineering Research Council of Canada","keywords":"Hagfish; Excretion; Ammonia; Chemistry; Amiloride; Apical membrane; Biophysics; Biochemistry; Sodium; Membrane; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00266306,0.002206397,0.001831204,0.0003953624,0.003145302,0.0004604296,0.004991253,0.0009373675,0.0004265896],"category_scores_gemma":[0.00146533,0.001340507,0.001150482,0.004092492,0.002134786,0.001106007,0.002503347,0.004618515,0.001024491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001189293,"about_ca_system_score_gemma":0.0001413388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005279973,"about_ca_topic_score_gemma":0.00008717447,"domain_scores_codex":[0.9834551,0.004584508,0.002018479,0.003516831,0.002886905,0.003538213],"domain_scores_gemma":[0.9877167,0.007874816,0.001046106,0.002617496,0.0001322098,0.0006126401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0006769404,0.004162654,0.001816801,0.0001041166,0.0002981377,0.0002581984,0.03635284,0.1951361,0.7079364,0.0004675647,0.03102285,0.0217674],"study_design_scores_gemma":[0.008041496,0.00963038,0.1404312,0.000589015,0.000836143,0.0003025979,0.1549354,0.4586104,0.1496251,0.0270435,0.0459289,0.004025972],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872339,0.0003472894,0.0001035423,0.003134463,0.0001590943,0.003427832,0.0006472568,0.0004256505,0.004520993],"genre_scores_gemma":[0.9866497,0.0007211295,0.0001467565,0.007475318,0.0006484615,0.002988399,0.001057742,0.0001790933,0.0001334059],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5583113,"threshold_uncertainty_score":0.9997534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01735554203232983,"score_gpt":0.2086935512089929,"score_spread":0.191338009176663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}