{"id":"W4281665436","doi":"10.3389/ftox.2022.893050","title":"Impact of in Utero Rat Exposure to 17Alpha-Ethinylestradiol or Genistein on Testicular Development and Germ Cell Gene Expression","year":2022,"lang":"en","type":"article","venue":"Frontiers in Toxicology","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Fonds de recherche du Québec; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Biology; In utero; Andrology; Offspring; Sertoli cell; Germ cell; Endocrinology; Internal medicine; Ethinylestradiol; Genistein; Fetus; Gene expression; Transcriptome; Testosterone (patch); Gene; Spermatogenesis; Population; Pregnancy; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007961627,0.0003473879,0.0003011783,0.0002885211,0.0001804102,0.0002921021,0.0001837234,0.0001929129,0.002366342],"category_scores_gemma":[0.00006749673,0.0001732168,0.0002616193,0.0001714265,0.0002998395,0.0001301554,0.0001694503,0.0004146668,0.0003160657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003407885,"about_ca_system_score_gemma":0.0004179346,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002741942,"about_ca_topic_score_gemma":0.007033642,"domain_scores_codex":[0.9998883,0.00001247934,0.000005402628,0.00004004099,0.00002012902,0.00003363366],"domain_scores_gemma":[0.9998871,0.00001452289,0.00003419496,0.00001311605,0.000009800205,0.00004125289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009817795,0.00008362289,0.001434897,0.00002911574,0.00001927048,0.00009352566,0.00003587984,0.00006269712,0.9954095,0.00004072781,0.00005716449,0.001751809],"study_design_scores_gemma":[0.00002833826,0.002124446,0.03125324,0.000007247392,0.00007118166,0.0002078772,0.0001515922,0.0001979064,0.9637386,0.00003582978,0.002176349,0.00000729842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967727,0.0008477476,0.000531574,0.00006493407,0.00003693898,0.00001135706,0.0006809778,0.00005167603,0.001002064],"genre_scores_gemma":[0.9872158,0.001723944,0.0006931729,0.00009189461,0.00001689919,0.00003965318,0.001515038,0.00004786043,0.00865563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002741942,"threshold_uncertainty_score":0.007916152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01034212258904282,"score_gpt":0.3001105966654387,"score_spread":0.2897684740763959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}