{"id":"W4281666800","doi":"10.1111/jeu.12927","title":"The evolution of <scp>pre‐mRNA</scp> splicing and its machinery revealed by reduced extremophilic red algae","year":2022,"lang":"en","type":"article","venue":"Journal of Eukaryotic Microbiology","topic":"Genomics and Phylogenetic Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Northern British Columbia; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Tula Foundation","keywords":"Biology; Spliceosome; Intron; RNA splicing; Minor spliceosome; Group II intron; Algae; Genetics; Plastid; Green algae; Group I catalytic intron; Evolutionary biology; Botany; Gene; RNA; Chloroplast","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000678429,0.0001557331,0.0003059694,0.00006637649,0.0002739478,0.000008229606,0.0003154092,0.00008776056,0.000005744944],"category_scores_gemma":[0.0002368827,0.0001192391,0.0001314098,0.00009564646,0.0001142533,0.000001401704,0.0003250512,0.0002176992,4.07714e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005369806,"about_ca_system_score_gemma":0.0001124606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001510291,"about_ca_topic_score_gemma":0.000006198565,"domain_scores_codex":[0.9986393,0.0002694983,0.0005546316,0.0002120608,0.00006813326,0.0002563372],"domain_scores_gemma":[0.9988694,0.0001284693,0.0006004085,0.0002022711,0.000141304,0.00005812325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008438466,0.0000407105,0.004904938,0.00001466656,0.0001860766,0.000002829477,0.0001050651,0.0001367941,0.984149,0.00004008492,0.01007755,0.000257934],"study_design_scores_gemma":[0.00649257,0.007396081,0.1460321,0.00009329834,0.0005930972,0.007697836,0.003194415,0.0003450848,0.707122,0.002238041,0.1182039,0.0005916327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9572715,0.04157251,0.00004325281,0.0003455461,0.0004350771,0.0001394627,0.00005827106,0.00000115271,0.0001332149],"genre_scores_gemma":[0.9968694,0.00198804,0.0001457989,0.0001014498,0.0001666344,0.000004620863,0.0000160495,0.00001663991,0.0006913825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.277027,"threshold_uncertainty_score":0.4862429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006423575922238221,"score_gpt":0.2105718542703552,"score_spread":0.204148278348117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}