{"id":"W4281667423","doi":"10.3390/polym14112240","title":"Perfluorocarbon Nanodroplets for Dual Delivery with Ultrasound/GSH-Responsive Release of Model Drug and Passive Release of Nitric Oxide","year":2022,"lang":"en","type":"article","venue":"Polymers","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Korea Research Institute of Chemical Technology; Ministry of Trade, Industry and Energy","keywords":"Nanocarriers; Drug delivery; Amphiphile; Glutathione; Nitric oxide; Polymersome; Nanotechnology; Copolymer; Chemistry; Drug; Combinatorial chemistry; Small molecule; Biophysics; Materials science; Organic chemistry; Pharmacology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002008802,0.0003802951,0.0001622627,0.0002140885,0.0001334985,0.0001445829,0.0001954975,0.0004276622,0.0005369313],"category_scores_gemma":[0.0001712865,0.0001423348,0.000198977,0.0001075985,0.0001616672,0.0003411648,0.0001634593,0.0003503524,0.0002596044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003429299,"about_ca_system_score_gemma":0.0002006711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003085551,"about_ca_topic_score_gemma":0.0006600422,"domain_scores_codex":[0.9998853,0.00001253103,0.000008603562,0.00003233021,0.00004643627,0.00001472496],"domain_scores_gemma":[0.9998881,0.0000213646,0.00004521209,0.000009119997,0.00001752647,0.0000187409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001294008,0.00001090634,0.00001528786,0.00002297698,0.000001442016,0.000023083,0.000006265117,0.00005937429,0.9984413,0.00009813132,0.00002970996,0.001278596],"study_design_scores_gemma":[0.000005026223,0.00007991574,0.0001178264,0.000001746571,0.000003580762,0.0000545383,0.000001669988,0.0005470894,0.997912,0.00001478462,0.001258946,0.000002926702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9393069,0.004510035,0.051985,0.0003262567,0.0001545332,0.0001722886,0.0003143759,0.0003207361,0.002909866],"genre_scores_gemma":[0.9407828,0.002463092,0.05220728,0.0001903809,0.00005325743,0.0001853441,0.0002702413,0.00005740062,0.003790239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005369313,"threshold_uncertainty_score":0.002488196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005990667159712727,"score_gpt":0.1858380721640544,"score_spread":0.1798474050043417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}