{"id":"W4281674598","doi":"10.1200/jco.2022.40.16_suppl.508","title":"Historical early treatment effects of adjuvant endocrine therapy for breast cancer in high-risk subgroups: Reanalysis of BIG 1-98, SOFT and TEXT.","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Breast cancer; Internal medicine; Tamoxifen; Hazard ratio; Oncology; Adjuvant; Randomization; Relative risk; Clinical trial; Randomized controlled trial; Cancer; Gynecology; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001232671,0.0001780664,0.00259045,0.0002996636,0.00004079859,0.000001677184,0.0001367764,0.0001131069,0.0001024206],"category_scores_gemma":[0.0005944874,0.0001235309,0.0005678508,0.0002739399,0.0001785957,0.00005630402,0.00004695236,0.0005328227,1.552886e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001262746,"about_ca_system_score_gemma":0.0008830452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001962844,"about_ca_topic_score_gemma":0.0002559885,"domain_scores_codex":[0.996537,0.0005165494,0.002092781,0.0002398723,0.0003777325,0.0002360438],"domain_scores_gemma":[0.9931068,0.003677561,0.002490038,0.0002136903,0.0003139167,0.0001979246],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.01959715,0.002272928,0.3159731,0.00005194214,0.0009894667,0.0001428761,0.0002316141,0.0001482011,0.001081093,0.00002281461,0.00004374997,0.659445],"study_design_scores_gemma":[0.03404406,0.04002469,0.9031892,0.00009093035,0.001056635,0.0002536175,0.00009854653,0.00005463378,0.0004810933,0.0006296939,0.0199653,0.000111584],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834745,0.010985,0.000384266,0.003828634,0.0008347721,0.0004162535,0.00005920502,0.000004988522,0.00001240171],"genre_scores_gemma":[0.9900331,0.007362251,0.001481099,0.0002201565,0.000652404,0.00007158172,0.000001390805,0.00002575804,0.0001522044],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6593335,"threshold_uncertainty_score":0.5037445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04465586979195556,"score_gpt":0.4023459941710787,"score_spread":0.3576901243791231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}