{"id":"W4281675779","doi":"10.1200/edbk_350358","title":"Personalizing Adjuvant Endocrine Therapy for Early-Stage Hormone Receptor–Positive Breast Cancer","year":2022,"lang":"en","type":"article","venue":"American Society of Clinical Oncology Educational Book","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Endocrine system; Breast cancer; Oncology; Medicine; Adjuvant; Internal medicine; Hormone receptor; Adjuvant therapy; Stage (stratigraphy); Medical prescription; Hormone; Cancer; Gynecology; Pharmacology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000537851,0.0002436815,0.0002043284,0.0003551333,0.0002461186,0.0006508721,0.0002528522,0.0005359146,0.008769205],"category_scores_gemma":[0.001220087,0.00008513906,0.0002037414,0.0002801786,0.0002819088,0.0008462612,0.000487236,0.001845118,0.002408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003853764,"about_ca_system_score_gemma":0.000450962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007109457,"about_ca_topic_score_gemma":0.004404059,"domain_scores_codex":[0.9998411,0.0000525438,0.00000840086,0.00001011391,0.00007553978,0.00001236823],"domain_scores_gemma":[0.9997618,0.0001349567,0.00002172802,0.000008329499,0.00003474582,0.00003842712],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006201614,0.0001328207,0.0007927506,0.0004738956,0.00001374089,0.000261468,0.0002464649,0.0004371841,0.002507685,0.008684247,0.4319799,0.5544078],"study_design_scores_gemma":[0.00002139116,0.00008772893,0.001589633,0.0004089495,0.00001324832,0.0008026116,0.0000884352,0.0002720362,0.0004310387,0.003980663,0.9922957,0.000008539251],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.01466465,0.4235296,0.01932118,0.2241994,0.03406603,0.0001393847,0.0004162019,0.0007433114,0.2829202],"genre_scores_gemma":[0.0709092,0.5251412,0.02653551,0.0874358,0.03839123,0.0001272404,0.000457006,0.0001470053,0.2508558],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.008769205,"threshold_uncertainty_score":0.02933592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0643257032058528,"score_gpt":0.455452952006897,"score_spread":0.3911272488010442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}