{"id":"W4281677430","doi":"10.1200/jco.2022.40.16_suppl.e19024","title":"Changes in health-related quality of life in patients with newly diagnosed acute myeloid leukemia receiving ivosidenib + azacitidine or placebo + azacitidine.","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; Azacitidine; Quality of life (healthcare); Placebo; Clinical endpoint; Internal medicine; Myeloid leukemia; Clinical trial; Oncology; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008878291,0.0003503115,0.001076071,0.0001916262,0.0001878221,0.0003451388,0.0002317932,0.000469177,0.001951045],"category_scores_gemma":[0.001110558,0.0001823734,0.0007551397,0.0002625526,0.0002908416,0.0003576853,0.0002348179,0.0009130681,0.0001857188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003985678,"about_ca_system_score_gemma":0.0002952857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005815197,"about_ca_topic_score_gemma":0.001328036,"domain_scores_codex":[0.9996732,0.0001618082,0.00002628607,0.00004525185,0.00003763679,0.00005572175],"domain_scores_gemma":[0.9994833,0.0001595675,0.0001579881,0.00001803674,0.00001874268,0.0001623004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7298191,0.01765983,0.1300343,0.0008760059,0.002449389,0.0002715474,0.0002633401,0.001711946,0.02002892,0.00009462265,0.001532968,0.09525815],"study_design_scores_gemma":[0.1162851,0.407845,0.4675179,0.00006833881,0.001464264,0.0003946162,0.0001583438,0.001528174,0.00240091,0.0001362434,0.002158949,0.00004208726],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978274,0.001368487,0.00005186319,0.00007420195,0.00003239795,0.0001179974,0.0002071483,0.000005149501,0.00031551],"genre_scores_gemma":[0.998551,0.0004361961,0.0001540497,0.0001243195,0.00003759121,0.0001738744,0.0002878105,0.000001176139,0.0002340204],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001951045,"threshold_uncertainty_score":0.006526887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1087377732854438,"score_gpt":0.4292250670593482,"score_spread":0.3204872937739043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}