{"id":"W4281690021","doi":"10.1093/neuonc/noac079.074","title":"DIPG-17. CD155 regulates cell growth and immune evasion in diffuse intrinsic pontine glioma","year":2022,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Cancer research; Immune checkpoint; Biology; Immune system; CD137; IL-2 receptor; Immunotherapy; Glioma; T cell; CD86; CD44; Immunology; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005730566,0.0003290829,0.0006656224,0.0005396177,0.00050537,0.00001887294,0.0004474623,0.0003176512,0.001059796],"category_scores_gemma":[0.0002027738,0.0003215889,0.0001283874,0.0004979155,0.0003615931,0.0001305115,0.0006798113,0.001053373,0.00007836153],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001483447,"about_ca_system_score_gemma":0.0001621287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002090987,"about_ca_topic_score_gemma":0.00001788302,"domain_scores_codex":[0.9962938,0.001760586,0.0006511578,0.0005672662,0.00006994987,0.000657251],"domain_scores_gemma":[0.9981647,0.001033146,0.0002723218,0.0004585106,0.00004067391,0.00003070345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004208964,0.001186041,0.0009381672,0.00001756525,0.00005370155,0.0002538923,0.001215958,0.000003677665,0.9791257,0.0002539101,0.001740899,0.01100148],"study_design_scores_gemma":[0.01224062,0.003853783,0.01438437,0.00001257081,0.00004274018,0.001747012,0.0006949549,0.000005238471,0.7187939,0.0002569511,0.2475849,0.0003829154],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9775226,0.01670047,0.000003169805,0.001946791,0.00137719,0.0004687717,0.00002138804,0.0001071265,0.0018525],"genre_scores_gemma":[0.9964744,0.00106721,0.00003228031,0.0011343,0.00003242808,0.0001334172,0.00008060869,0.00005058655,0.0009947571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2603318,"threshold_uncertainty_score":0.9999236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00853908833374474,"score_gpt":0.2294334595570016,"score_spread":0.2208943712232568,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}