{"id":"W4281692222","doi":"10.23958/ijirms/vol07-i06/1418","title":"Evidence For Cannabidiol Modulation of Serotonergic Transmission in a Model of Osteoarthritis via in vivo PET Imaging and Behavioral Assessment","year":2022,"lang":"en","type":"article","venue":"International Journal of Innovative Research in Medical Science","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Complementary and Integrative Health; National Institute on Drug Abuse; National Institute on Aging; RTI International; School of Medicine, New York University; National Institutes of Health; Center for Advanced Imaging Innovation and Research; National Institute of Biomedical Imaging and Bioengineering; York University","keywords":"Serotonergic; Medicine; Neurochemical; Pharmacology; Anxiolytic; Analgesic; Chronic pain; Neuroimaging; Serotonin; Psychology; Neuroscience; Internal medicine; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003663822,0.0007038722,0.0004584958,0.0005890491,0.0002706368,0.0003047106,0.0004157093,0.0004545529,0.002209564],"category_scores_gemma":[0.0002088042,0.0002660547,0.0004276745,0.0002654026,0.0005638088,0.0004076584,0.0001708202,0.0009482697,0.0004784601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005179193,"about_ca_system_score_gemma":0.0005071809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002522426,"about_ca_topic_score_gemma":0.005289431,"domain_scores_codex":[0.9997519,0.00003357763,0.000022514,0.00005515959,0.00006953222,0.00006736531],"domain_scores_gemma":[0.9997086,0.00002699273,0.00009998199,0.00003937774,0.0000653541,0.00005974714],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008582755,0.0003288881,0.0003876108,0.0001270963,0.00002411383,0.0001152962,0.00002434768,0.00002257116,0.9956186,0.00007120224,0.00005952694,0.00236242],"study_design_scores_gemma":[0.0001416626,0.00730301,0.01939814,0.00004546229,0.0002069487,0.001183267,0.0001545407,0.0009624095,0.9681628,0.0001483127,0.00227218,0.0000212811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9743153,0.006982135,0.01384988,0.0005135807,0.0001713679,0.000227289,0.0007493655,0.000170719,0.003020408],"genre_scores_gemma":[0.9761209,0.005604062,0.009201718,0.000311758,0.00006494061,0.0003639477,0.0007946324,0.00004000402,0.007498091],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002522426,"threshold_uncertainty_score":0.007391751,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1329273746412234,"score_gpt":0.5110431846975138,"score_spread":0.3781158100562904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}