{"id":"W4281694566","doi":"10.1007/s13311-022-01251-6","title":"Updates in IDH-Wildtype Glioblastoma","year":2022,"lang":"en","type":"review","venue":"Neurotherapeutics","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Glioblastoma; Neurology; Medicine; Neurosurgery; Wild type; Brain tumor; Oncology; Internal medicine; Bioinformatics; Neuroscience; Cancer research; Biology; Pathology; Gene; Surgery; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007585171,0.0009046834,0.001758363,0.002755609,0.0001843599,0.00116007,0.0007414006,0.001090844,0.00579054],"category_scores_gemma":[0.001773082,0.0003297504,0.0008988497,0.002265431,0.0003781482,0.001378893,0.0008290499,0.001707679,0.001744019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009137832,"about_ca_system_score_gemma":0.001578847,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001955121,"about_ca_topic_score_gemma":0.005654589,"domain_scores_codex":[0.9997876,0.00004421148,0.00004984221,0.0000316342,0.00005907444,0.00002762871],"domain_scores_gemma":[0.9994119,0.0002795367,0.0001229334,0.00001552697,0.0001244738,0.0000455708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000203558,0.00003670698,0.0001645501,0.02675103,0.0001903471,0.0001875649,0.00003983714,0.0003221823,0.0008130274,0.001772599,0.08658574,0.8829329],"study_design_scores_gemma":[0.0001027425,0.0001428563,0.0007239192,0.01130023,0.0007956436,0.0009488531,0.00003470434,0.0001278995,0.0003211025,0.001474662,0.9840032,0.0000241757],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001031878,0.9976514,0.00008141271,0.0005384058,0.000620215,0.000005512083,0.00006689506,0.00001186309,0.0009211985],"genre_scores_gemma":[0.0007322836,0.9965694,0.000165458,0.001145688,0.0005247423,0.000008278691,0.0001036835,0.000003706162,0.0007466881],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00579054,"threshold_uncertainty_score":0.01937127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09257305351057138,"score_gpt":0.3710001645915484,"score_spread":0.2784271110809771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}