{"id":"W4281700837","doi":"10.3233/jpd-213126","title":"Evaluating the Use of Digital Biomarkers to Test Treatment Effects on Cognition and Movement in Patients with Lewy Body Dementia","year":2022,"lang":"en","type":"article","venue":"Journal of Parkinson s Disease","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of California, Irvine; University of South Carolina; Thomas Jefferson University; Ottawa Hospital Research Institute; Georgetown University; University of Wisconsin-Madison; University of Southern California; Eli Lilly and Company","keywords":"Dementia with Lewy bodies; Dementia; Lewy body; Cognition; Test (biology); Movement (music); Lewy body disease; Psychology; Medicine; Physical medicine and rehabilitation; Psychiatry; Internal medicine; Disease; Art","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001725853,0.0001811187,0.0002738251,0.000237102,0.0001124233,0.00004180867,0.00005635538,0.00001332692,0.00003382345],"category_scores_gemma":[0.0001850098,0.0001109351,0.0001050218,0.0002112625,0.00002116511,0.0001392515,0.00004803649,0.0000820143,0.000001560807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002667348,"about_ca_system_score_gemma":0.0001496739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001230788,"about_ca_topic_score_gemma":0.000002490773,"domain_scores_codex":[0.9983742,0.0001123057,0.0003487447,0.0002016866,0.0007811061,0.0001819931],"domain_scores_gemma":[0.9988198,0.0002233143,0.000322509,0.0001744149,0.0001127209,0.0003472448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01178082,0.006402635,0.9556639,0.00005218266,0.0007461155,0.0002510546,0.0001135065,0.0003245524,0.0004297243,0.000005610544,0.0001154262,0.02411447],"study_design_scores_gemma":[0.0115647,0.01892426,0.965425,0.0002504161,0.00127246,0.000004314097,0.00007167003,0.0003187406,0.0005504669,0.00005343248,0.001459674,0.0001048511],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980398,0.000244451,0.00001649853,0.000355152,0.00006918755,0.001043929,0.0002125103,0.000004855091,0.00001356193],"genre_scores_gemma":[0.9991746,0.00001946683,0.0002050792,0.0004056236,0.00002587369,0.00009027486,0.00004436654,0.00001966548,0.00001508313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02400962,"threshold_uncertainty_score":0.4523803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03566268630955795,"score_gpt":0.296559669012356,"score_spread":0.2608969827027981,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}