{"id":"W4281702819","doi":"10.1111/jch.14517","title":"Identifying and treating resistant hypertension in PRECISION: A randomized long‐term clinical trial with aprocitentan","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Hypertension","topic":"Blood Pressure and Hypertension Studies","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Victoria Hospital; London Health Sciences Centre","funders":"Idorsia Pharmaceuticals","keywords":"Medicine; Placebo; Randomization; Randomized controlled trial; Blood pressure; Internal medicine; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003192598,0.001551865,0.003424102,0.0006723102,0.0005437845,0.00115919,0.0009209079,0.002627936,0.003982361],"category_scores_gemma":[0.002401524,0.0008005527,0.002079336,0.0005761269,0.001453378,0.001127323,0.0005712302,0.002493212,0.0006220547],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005504211,"about_ca_system_score_gemma":0.001341179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007900154,"about_ca_topic_score_gemma":0.001611951,"domain_scores_codex":[0.9987981,0.0006308382,0.00009115032,0.0001753577,0.0001382555,0.0001662456],"domain_scores_gemma":[0.9986487,0.0004302909,0.0003343878,0.0001372617,0.00009371187,0.0003556825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9823593,0.004325176,0.0002403077,0.0004227716,0.000609334,0.000041038,0.00002655499,0.000130554,0.001971773,0.00006309274,0.0003324058,0.009477803],"study_design_scores_gemma":[0.9563569,0.04199006,0.00083944,0.00001695721,0.0002602264,0.00001598449,0.000005521553,0.0001016463,0.0001365392,0.0000439011,0.0002239303,0.000008827707],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9742726,0.01112532,0.001601602,0.001007011,0.001007555,0.007610854,0.001044993,0.000261971,0.002067983],"genre_scores_gemma":[0.9713604,0.006354378,0.003797616,0.002081495,0.00161161,0.009406037,0.001428962,0.00002879433,0.00393075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003982361,"threshold_uncertainty_score":0.01688433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1834213439228999,"score_gpt":0.4179743888352165,"score_spread":0.2345530449123165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}