{"id":"W4281703781","doi":"10.1182/blood.2021014853","title":"p57Kip2 regulates embryonic blood stem cells by controlling sympathoadrenal progenitor expansion","year":2022,"lang":"en","type":"article","venue":"Blood","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"National Health and Medical Research Council; Cambridge Institute for Medical Research, University of Cambridge; Blood Cancer UK; Medical Research Council; Wellcome Trust; Kay Kendall Leukaemia Fund; UK Research and Innovation","keywords":"Biology; Progenitor cell; Cell biology; Embryonic stem cell; Stem cell; Haematopoiesis; Neural crest; Mesenchymal stem cell; Dorsal aorta; Immunology; Cellular differentiation; Embryo; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003625051,0.0001672257,0.0001671373,0.00005071594,0.0003338177,0.00003631546,0.0004548014,0.0001091463,0.0000795751],"category_scores_gemma":[0.00003540234,0.0001662969,0.0001200474,0.0002087529,0.0001232288,0.000003669862,0.0003800465,0.0002246524,0.00002155787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001771828,"about_ca_system_score_gemma":0.0001908969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009804014,"about_ca_topic_score_gemma":0.00000186619,"domain_scores_codex":[0.9981467,0.000152538,0.0002404939,0.0005174797,0.0004856256,0.000457157],"domain_scores_gemma":[0.9990631,0.00003517487,0.00009438016,0.0004868839,0.0000776683,0.0002428094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004110568,0.0007659212,0.0002010423,0.00001453302,0.0001224764,0.00001094839,0.00002168367,0.00001071437,0.9919518,0.00002628239,0.005438059,0.00139544],"study_design_scores_gemma":[0.002397033,0.0005514792,0.00005048821,0.000006224071,0.00007946085,0.00004313437,0.00008986756,0.00007491869,0.9576563,0.00004118455,0.03881507,0.0001947862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951432,0.003214381,0.0002461514,0.0003462338,0.00007553693,0.000557199,0.0002543366,0.00004252134,0.0001204826],"genre_scores_gemma":[0.9966324,0.0001305674,0.0003559416,0.0001774136,0.0002471339,0.0006096252,0.0003190049,0.00004003224,0.001487881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03429544,"threshold_uncertainty_score":0.6781392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006866920499221385,"score_gpt":0.2332897136900592,"score_spread":0.2264227931908378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}