{"id":"W4281703831","doi":"10.1136/annrheumdis-2021-221801","title":"The 2021 EULAR/American College of Rheumatology points to consider for diagnosis, management and monitoring of the interleukin-1 mediated autoinflammatory diseases: cryopyrin-associated periodic syndromes, tumour necrosis factor receptor-associated periodic syndrome, mevalonate kinase deficiency, and deficiency of the interleukin-1 receptor antagonist","year":2022,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":135,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; University of Toronto; Children's Hospital of Western Ontario; Lawson Health Research Institute; Alberta Children's Hospital; Western University","funders":"Chugai Pharmaceutical; EMD Serono; National Institutes of Health; Idorsia Pharmaceuticals; Swedish Orphan Biovitrum; European League Against Rheumatism; Ablynx; Regeneron Pharmaceuticals; Celgene; Biogen; Sanofi; Amgen; Pfizer; AstraZeneca; Eli Lilly and Company","keywords":"Medicine; Rheumatology; Tumor necrosis factor alpha; Internal medicine; Pathology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004405512,0.001379133,0.001916531,0.00211581,0.001544878,0.003194978,0.001167121,0.008118559,0.01459659],"category_scores_gemma":[0.007117373,0.0004509786,0.001271762,0.001287337,0.001201837,0.001288382,0.001307621,0.006085269,0.0142332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001195008,"about_ca_system_score_gemma":0.00438019,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003707831,"about_ca_topic_score_gemma":0.01126844,"domain_scores_codex":[0.9959421,0.0007826547,0.0007242795,0.0002118899,0.001597812,0.0007413683],"domain_scores_gemma":[0.9900225,0.0008033897,0.001359074,0.0003908246,0.005272725,0.002151452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004964311,0.0003589199,0.008481184,0.0006610755,0.00009113085,0.003380403,0.00006965216,0.000269986,0.003800381,0.002264033,0.7804841,0.1996428],"study_design_scores_gemma":[0.0003385543,0.0003097258,0.03913817,0.001838382,0.00008402316,0.006086838,0.0002142343,0.0003464766,0.001221776,0.001884904,0.9484587,0.00007824488],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.01718449,0.06783158,0.01636944,0.548858,0.09386486,0.001770851,0.003772799,0.001339992,0.249008],"genre_scores_gemma":[0.139974,0.06915015,0.1429171,0.2498735,0.1370175,0.002710782,0.01157226,0.0007775543,0.2460074],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.01459659,"threshold_uncertainty_score":0.04883045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01232660050692919,"score_gpt":0.2543578670574643,"score_spread":0.2420312665505351,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}