{"id":"W4281706947","doi":"10.1002/ana.26429","title":"Progressive White Matter Injury in Preclinical Dutch Cerebral Amyloid Angiopathy","year":2022,"lang":"en","type":"article","venue":"Annals of Neurology","topic":"Intracerebral and Subarachnoid Hemorrhage Research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"National Institute of Biomedical Imaging and Bioengineering; National Center for Research Resources; National Institute of Neurological Disorders and Stroke; National Institute on Aging; National Health and Medical Research Council; National Cancer Institute; National Institutes of Health; Centre d'Imagerie BioMédicale; Alzheimer's Society; Massachusetts General Hospital","keywords":"Cerebral amyloid angiopathy; White matter; Medicine; Pathology; Neuroimaging; Amyloid (mycology); Intracerebral hemorrhage; Cohort; Hyperintensity; Magnetic resonance imaging; Internal medicine; Radiology; Disease; Dementia; Psychiatry; Subarachnoid hemorrhage","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005525824,0.0003193467,0.0002246154,0.0005876992,0.0003525939,0.0005694759,0.0002513046,0.0003780518,0.001288228],"category_scores_gemma":[0.001972155,0.00018873,0.000120733,0.0004256585,0.0003775164,0.0004809822,0.0004493893,0.0003053845,0.0002442547],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003902173,"about_ca_system_score_gemma":0.0003968074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01065558,"about_ca_topic_score_gemma":0.01014455,"domain_scores_codex":[0.9998282,0.00004737315,0.00001969385,0.00004848649,0.00002861494,0.00002756947],"domain_scores_gemma":[0.9992968,0.000107867,0.000332485,0.00003557547,0.00009688692,0.0001304486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006653629,0.0001280241,0.9868928,0.00002658197,0.00004861231,0.00160601,0.0003738303,0.00008240199,0.006841308,0.0001020267,0.0001383497,0.003094723],"study_design_scores_gemma":[0.000008002604,0.0001994663,0.9971897,0.000008275064,0.0000110994,0.001621268,0.0001134895,0.0001598183,0.0004515704,0.00007358047,0.0001603083,0.000003402537],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991751,0.0001346678,0.00007549839,0.00002226021,0.000002301318,0.000007979739,0.0001069043,0.000002582149,0.0004727663],"genre_scores_gemma":[0.9993808,0.00009549625,0.0001070637,0.00001607424,0.000003838994,0.000006098377,0.0001648124,0.000002213726,0.00022366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01065558,"threshold_uncertainty_score":0.02118713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05933301825544121,"score_gpt":0.3773934139146168,"score_spread":0.3180603956591757,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}