{"id":"W4281710986","doi":"10.1097/shk.0000000000001949","title":"ACTIVATION OF THE MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN (MAVS) FOLLOWING LIVER ISCHEMIA/REPERFUSION AND ITS EFFECT ON INFLAMMATION AND INJURY","year":2022,"lang":"en","type":"article","venue":"Shock","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Inflammation; Mitophagy; Reperfusion injury; Cell biology; Oxidative stress; Liver injury; Knockout mouse; In vivo; Signal transduction; Gene silencing; Apoptosis; Biology; Immunology; Autophagy; Ischemia; Pharmacology; Medicine; Receptor; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001983164,0.00009214383,0.0001283011,0.0000598391,0.0002862732,0.000007915574,0.00007318558,0.00007496662,0.00006939822],"category_scores_gemma":[0.000144871,0.00006767496,0.00005502903,0.00006774316,0.00003251643,0.00007746243,0.0001641267,0.0002370432,0.000005476121],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002659627,"about_ca_system_score_gemma":0.00002212106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001606001,"about_ca_topic_score_gemma":5.548183e-7,"domain_scores_codex":[0.9991406,0.0004242824,0.0001402103,0.0001437685,0.00004506113,0.0001060663],"domain_scores_gemma":[0.9996778,0.0001156927,0.00008827676,0.00009872716,0.00001493032,0.000004525338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001534361,0.0000136095,0.0001081752,0.00002354758,0.00003258113,6.153498e-7,0.0004482987,0.000001546749,0.9886749,0.00006871288,0.00004228162,0.009051304],"study_design_scores_gemma":[0.0007467392,0.0007498455,0.0002886686,0.00007984505,0.00001716966,0.000005897226,0.00009793259,0.00002926006,0.9966161,0.00001404261,0.001281749,0.00007270594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985853,0.0004224345,0.000007896799,0.00007813858,0.000323189,0.0004507353,0.000005351421,0.00001420402,0.0001126817],"genre_scores_gemma":[0.9990771,0.000005524296,0.000009292818,0.00002278462,0.00002266247,0.00002474939,0.00001019472,0.000007761031,0.0008199086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008978598,"threshold_uncertainty_score":0.2759705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006453975514099999,"score_gpt":0.2216968275078963,"score_spread":0.2152428519937963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}