{"id":"W4281710986","doi":"10.1097/shk.0000000000001949","title":"ACTIVATION OF THE MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN (MAVS) FOLLOWING LIVER ISCHEMIA/REPERFUSION AND ITS EFFECT ON INFLAMMATION AND INJURY","year":2022,"lang":"en","type":"article","venue":"Shock","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Inflammation; Mitophagy; Reperfusion injury; Cell biology; Oxidative stress; Liver injury; Knockout mouse; In vivo; Signal transduction; Gene silencing; Apoptosis; Biology; Immunology; Autophagy; Ischemia; Pharmacology; Medicine; Receptor; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001727851,0.0003557614,0.0002865906,0.0001739608,0.0001095745,0.0002189206,0.0001183546,0.0002753529,0.001205986],"category_scores_gemma":[0.0001018332,0.00008659687,0.0003387034,0.0001106164,0.0002299086,0.0001908556,0.0001540198,0.0004075918,0.0002119973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002173355,"about_ca_system_score_gemma":0.0001266795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001655045,"about_ca_topic_score_gemma":0.0001766836,"domain_scores_codex":[0.9998933,0.00002067282,0.00001152326,0.00001926994,0.00002151912,0.00003363983],"domain_scores_gemma":[0.999905,0.000008653186,0.00003958362,0.000008143107,0.00001315474,0.00002556856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005757481,0.00003442333,0.0003194519,0.0000687936,0.00001020739,0.00004408698,0.00001269841,0.00002634171,0.9978276,0.00003935087,0.00003202472,0.001009187],"study_design_scores_gemma":[0.0000274255,0.001079662,0.01071873,0.00000999588,0.0000351951,0.0001949771,0.0000450086,0.0004460884,0.9865328,0.00004578702,0.000859596,0.000004666149],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930587,0.004181217,0.001764201,0.0001516466,0.00005513315,0.00002564326,0.0001856693,0.00005364741,0.0005241015],"genre_scores_gemma":[0.9965971,0.001115557,0.0008349403,0.00005780443,0.00001917527,0.00003404385,0.000244926,0.000007456948,0.001088913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001205986,"threshold_uncertainty_score":0.0040344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006453975514099999,"score_gpt":0.2216968275078963,"score_spread":0.2152428519937963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}