{"id":"W4281719350","doi":"10.1001/jamanetworkopen.2022.16191","title":"The Timing of Cancer Drug Approvals in the United States and Europe","year":2022,"lang":"en","type":"letter","venue":"JAMA Network Open","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Anticancer drug; Medicine; Drug; Library science; History; Family medicine; Pharmacology; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.03943679,0.000251004,0.00104452,0.0001921264,0.0005171646,0.0005779281,0.001895594,0.0001945735,0.0006707505],"category_scores_gemma":[0.001053498,0.0002080409,0.00007424847,0.0006698339,0.0001308403,0.0002530593,0.0006203707,0.001371706,0.00008016082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002397121,"about_ca_system_score_gemma":0.000171421,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02278706,"about_ca_topic_score_gemma":0.001458787,"domain_scores_codex":[0.9929758,0.002417324,0.003319114,0.0005837088,0.0001505455,0.0005535502],"domain_scores_gemma":[0.9897745,0.005998531,0.003306534,0.0008189286,0.00006058947,0.00004087395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001869952,0.00001039778,0.009559115,0.0001882451,0.00008469539,0.000004750572,0.002557889,0.003026715,4.882468e-9,0.003351318,0.9809902,0.0002079677],"study_design_scores_gemma":[0.0003774876,0.00002478364,0.005915852,0.0001711983,0.00001150095,0.000002295951,0.001023379,0.006426095,3.946714e-8,0.004592961,0.9812185,0.0002358926],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01520804,0.01171532,0.0000161262,0.9630121,0.0007041094,0.001967815,0.0004777466,0.00001097625,0.006887782],"genre_scores_gemma":[0.001176295,0.009501297,0.000232548,0.9785241,0.002673622,0.0009692708,0.0006536001,0.0000842131,0.006185005],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03838329,"threshold_uncertainty_score":0.9891019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3128999770212813,"score_gpt":0.4209615251897986,"score_spread":0.1080615481685174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}