{"id":"W4281722646","doi":"10.1200/jco.2022.40.16_suppl.7061","title":"Thrombocytopenic myelofibrosis (MF) patients previously treated with a JAK inhibitor in a phase 3 randomized study of momelotinib (MMB) versus danazol (DAN) [MOMENTUM].","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sierra Wireless (Canada); Princess Margaret Cancer Centre","funders":"Sierra Oncology","keywords":"Medicine; Myelofibrosis; Gastroenterology; Internal medicine; Placebo; Clinical endpoint; Anemia; Danazol; Randomization; Randomized controlled trial; Surgery; Bone marrow; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001573511,0.001106505,0.001995197,0.0002744214,0.0004756609,0.001109794,0.0005635488,0.001151189,0.007079083],"category_scores_gemma":[0.001333668,0.0006588406,0.001223542,0.0002620171,0.0006174574,0.0008371163,0.0003750081,0.002441725,0.0007957284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005827522,"about_ca_system_score_gemma":0.001251608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008053235,"about_ca_topic_score_gemma":0.002632335,"domain_scores_codex":[0.9996295,0.0001919586,0.0000212727,0.0000557209,0.00002433609,0.00007720441],"domain_scores_gemma":[0.9994366,0.0001088081,0.000109121,0.00002919177,0.00003097822,0.0002853425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9700062,0.008483417,0.0016728,0.0003290733,0.0006485381,0.00008652313,0.00004497742,0.0002769089,0.003604905,0.0001144882,0.00161893,0.01311318],"study_design_scores_gemma":[0.911305,0.08224843,0.004427274,0.00003807218,0.0003743841,0.00005898405,0.00002059487,0.0003406577,0.0002149002,0.0001241979,0.0008361096,0.00001151973],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861341,0.002872713,0.0004751996,0.001032628,0.0003650775,0.005184554,0.001395465,0.00009718865,0.002443032],"genre_scores_gemma":[0.9865487,0.001686809,0.001177093,0.001988928,0.0003868984,0.004068764,0.001357385,0.00001710595,0.002768175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007079083,"threshold_uncertainty_score":0.02368194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09404202623910829,"score_gpt":0.4406790425051299,"score_spread":0.3466370162660216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}