{"id":"W4281730292","doi":"10.1016/j.csbj.2022.05.041","title":"Secondary structures in RNA synthesis, splicing and translation","year":2022,"lang":"en","type":"review","venue":"Computational and Structural Biotechnology Journal","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Human Genome Research Institute","keywords":"RNA splicing; Protein secondary structure; RNA; Translation (biology); Nucleic acid secondary structure; Computational biology; Messenger RNA; Biology; Nucleic acid structure; Genetics; Cell biology; Chemistry; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002229264,0.0002554009,0.0005175841,0.0003718025,0.0003149248,0.00006531117,0.0002052824,0.0004108985,0.00006162882],"category_scores_gemma":[0.00008229989,0.0002060846,0.0001104223,0.0001483688,0.0001811823,0.000009392114,0.0001612445,0.001022837,3.576514e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003846994,"about_ca_system_score_gemma":0.000204763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006370275,"about_ca_topic_score_gemma":0.00000852514,"domain_scores_codex":[0.9986553,0.0001546436,0.0004102483,0.0003643231,0.0001564772,0.0002590479],"domain_scores_gemma":[0.9994943,0.0001104557,0.0001900423,0.0001016918,0.00002022392,0.00008328072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001662763,0.000002326949,0.00001467347,0.0003991971,0.00007364245,0.00002713697,0.00001076333,0.00006549458,0.0003933037,0.0002735387,0.00003086835,0.9986925],"study_design_scores_gemma":[0.001321146,0.0005556985,0.001167183,0.001285525,0.0002324717,0.01726663,0.0002552716,0.002187208,0.0003006432,0.01469496,0.9595263,0.001206975],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04007242,0.9591511,0.0002137247,0.0002036148,0.00009535164,0.0001813494,0.00004093419,0.000009240992,0.00003227418],"genre_scores_gemma":[0.009324827,0.9885416,0.001806231,0.00003660456,0.0001137876,0.00001249242,0.0001224839,0.00002118693,0.00002079837],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9974855,"threshold_uncertainty_score":0.8403885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02698611870781238,"score_gpt":0.3100155429524016,"score_spread":0.2830294242445893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}