{"id":"W4281732590","doi":"10.1200/jco.2022.40.16_suppl.tps7590","title":"frontMIND: A phase III, randomized, double-blind study of tafasitamab + lenalidomide + R-CHOP versus R-CHOP alone for newly diagnosed high-intermediate and high-risk diffuse large B-cell lymphoma.","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"MorphoSys","keywords":"Medicine; Lenalidomide; Internal medicine; CHOP; Diffuse large B-cell lymphoma; Vincristine; Oncology; Phases of clinical research; Clinical endpoint; Rituximab; Gastroenterology; Lymphoma; Randomized controlled trial; Clinical trial; Chemotherapy; Multiple myeloma; Cyclophosphamide","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002134409,0.002600133,0.002757111,0.0005732341,0.0004956907,0.001521722,0.001776713,0.001951272,0.01196298],"category_scores_gemma":[0.001577606,0.00100803,0.001946794,0.0005079454,0.001492017,0.001324393,0.0006092652,0.00397463,0.002298166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001176186,"about_ca_system_score_gemma":0.001807984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001221909,"about_ca_topic_score_gemma":0.002907219,"domain_scores_codex":[0.9994392,0.0002712221,0.00002301937,0.000116401,0.00004660495,0.0001036331],"domain_scores_gemma":[0.9992216,0.0001637163,0.0001548128,0.00007675037,0.00005874926,0.0003244144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9630792,0.01851095,0.0002700527,0.0005519906,0.0007215468,0.00002525503,0.00004311594,0.0003764294,0.003209884,0.0001462276,0.001327556,0.01173782],"study_design_scores_gemma":[0.9592678,0.03896321,0.0004325847,0.0000152343,0.0001864584,0.00001863541,0.00001092319,0.0002637396,0.0002014032,0.0001196772,0.0005121991,0.000008122381],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9619086,0.005334753,0.002148981,0.001542683,0.001583681,0.01723221,0.0049052,0.0005621181,0.004781784],"genre_scores_gemma":[0.9463536,0.004500448,0.005851309,0.003303207,0.0009294178,0.02419942,0.004655961,0.0001232022,0.01008342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01196298,"threshold_uncertainty_score":0.04002017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07088796854688545,"score_gpt":0.4139830785513839,"score_spread":0.3430951100044984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}