{"id":"W4281738335","doi":"10.1200/jco.2022.40.16_suppl.tps5624","title":"Trial in progress: Phase II activity trial of high-dose radiation and chemosensitization in patients with macrometastatic lymph node spread after sentinel node biopsy in vulvar cancer: Groningen International Study on Sentinel Nodes in Vulvar Cancer III (GROINSS-V III/NRG-GY024).","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"National Institutes of Health; KWF Kankerbestrijding","keywords":"Medicine; Vulvar cancer; Sentinel lymph node; Clinical endpoint; Sentinel node; Surgery; Radiation therapy; Supraclavicular lymph nodes; Primary tumor; Phases of clinical research; Cancer; Metastasis; Breast cancer; Internal medicine; Vulva; Chemotherapy; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002583993,0.002356209,0.002051564,0.0005276298,0.0004700771,0.001496573,0.001794667,0.00244287,0.007912538],"category_scores_gemma":[0.001261194,0.0005652391,0.0017773,0.0007141886,0.001491953,0.001269284,0.0005866466,0.003982633,0.001729131],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009903843,"about_ca_system_score_gemma":0.001988946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00173054,"about_ca_topic_score_gemma":0.003168585,"domain_scores_codex":[0.9992569,0.0004420391,0.00002336844,0.00009598639,0.00004679605,0.000134828],"domain_scores_gemma":[0.9991069,0.0001390508,0.0002095217,0.00009299706,0.00004101476,0.0004105301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.914321,0.02934205,0.003473291,0.0007138705,0.0009828319,0.0001393176,0.0002163427,0.001427828,0.01032127,0.0003910783,0.004107156,0.03456404],"study_design_scores_gemma":[0.8457358,0.1473318,0.003762505,0.00003932301,0.0002064682,0.00009718792,0.00004528688,0.0003355678,0.0006521597,0.000177548,0.00160314,0.00001322473],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9765879,0.004020137,0.001069259,0.001559036,0.0003758432,0.007076801,0.004906648,0.0002585141,0.004145857],"genre_scores_gemma":[0.9510421,0.004990237,0.004492747,0.002698335,0.000573857,0.01444378,0.01209069,0.000120095,0.009548189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007912538,"threshold_uncertainty_score":0.02647012,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04577754485668253,"score_gpt":0.4165883707451301,"score_spread":0.3708108258884475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}