{"id":"W4281745442","doi":"10.3389/fbioe.2022.866148","title":"The Hunt Is On! In Pursuit of the Ideal Stem Cell Population for Cartilage Regeneration","year":2022,"lang":"en","type":"review","venue":"Frontiers in Bioengineering and Biotechnology","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Élisabeth Bruyère Hospital; Ottawa Hospital; University of Ottawa","funders":"University of Ottawa","keywords":"Stem cell; Cartilage; Regeneration (biology); Progenitor cell; Medicine; Osteoarthritis; Stem-cell therapy; Regenerative medicine; Population; Biology; Cell biology; Pathology; Anatomy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000197447,0.0001759936,0.0005671394,0.0002835077,0.00007100025,0.000008397557,0.0001391582,0.0003757573,0.000001151043],"category_scores_gemma":[0.0000153104,0.0001079557,0.0001251082,0.0002865522,0.00004165754,0.00001108023,0.00005608363,0.0003057572,1.706552e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001695681,"about_ca_system_score_gemma":0.000032232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000104567,"about_ca_topic_score_gemma":0.00001902666,"domain_scores_codex":[0.9991205,0.00002921175,0.0003297197,0.0002256938,0.0001088233,0.0001860833],"domain_scores_gemma":[0.9995431,0.00003752632,0.0001210454,0.0002764245,0.000005981036,0.00001591492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002007121,0.00002436105,0.00004269416,0.001207262,0.00001460896,0.000003518253,0.00003313383,0.000008491614,0.0001331741,0.0007616962,0.0002946105,0.9974564],"study_design_scores_gemma":[0.0008628722,0.0008193591,0.00001431441,0.001673218,0.0001839069,0.00001863993,0.0001684909,0.0002471916,0.004637507,0.0001055073,0.9911082,0.0001607277],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002488322,0.9944367,0.0001785515,0.0005182317,0.0009719171,0.001316878,0.00004416678,0.00003144871,0.00001380211],"genre_scores_gemma":[0.00342912,0.9952133,0.0006922832,0.00001730681,0.00003340351,0.0002607144,0.00005866915,0.00002664859,0.000268551],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9972957,"threshold_uncertainty_score":0.4402305,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01799620840719933,"score_gpt":0.2471951349384268,"score_spread":0.2291989265312275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}