{"id":"W4281750849","doi":"10.1002/pros.24373","title":"Genomic biomarkers to guide precision radiotherapy in prostate cancer","year":2022,"lang":"en","type":"review","venue":"The Prostate","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; National Institutes of Health","keywords":"Prostate cancer; Prostate; Medicine; Radiation therapy; Cancer; Oncology; Prostate disease; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001294465,0.0005924036,0.001600899,0.000622966,0.0002240307,0.00007502595,0.0005543209,0.0001134354,0.001108102],"category_scores_gemma":[0.00006222998,0.0003346871,0.0004115594,0.001373228,0.0001324044,0.00006159968,0.0003592278,0.0008176682,0.0001174852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003026533,"about_ca_system_score_gemma":0.002008825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008907377,"about_ca_topic_score_gemma":0.00009514754,"domain_scores_codex":[0.9963512,0.0004435063,0.0008677833,0.000825859,0.0006383113,0.0008733015],"domain_scores_gemma":[0.9982187,0.0002697663,0.0002557413,0.0009349595,0.00005614779,0.0002647087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009221846,0.0001013422,0.0001578825,0.003837991,0.0005583426,0.0002362867,0.001461413,0.00001309952,0.0000285346,0.000002897322,0.01332398,0.9793561],"study_design_scores_gemma":[0.001657288,0.0004441252,0.00009391324,0.005231865,0.0003598865,0.00008071786,0.00007307821,0.00001810521,0.00001051194,0.00003564618,0.9916373,0.0003575304],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000408332,0.9849036,0.000001938516,0.002484917,0.000410652,0.01039514,0.0003852067,0.0001022468,0.0009079299],"genre_scores_gemma":[0.000004132653,0.9665042,0.0001937573,0.0004095339,0.0001649386,0.005504167,0.0002947017,0.0001868861,0.02673772],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9789985,"threshold_uncertainty_score":0.9999105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07174354759623408,"score_gpt":0.4222440753397179,"score_spread":0.3505005277434838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}