{"id":"W4281754242","doi":"10.1093/cvr/cvac066.072","title":"A preliminary study of patient-specific differences in induced pluripotent stem cell-derived cardiomyocytes following hypoxia-induced injury","year":2022,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Induced pluripotent stem cell; Medicine; Population; Homeobox protein NANOG; Hypoxia (environmental); Cardiomyopathy; Stem cell; Bioinformatics; Internal medicine; Cardiology; Heart failure; Biology; Embryonic stem cell; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009446083,0.0001767421,0.0002694817,0.000218133,0.0001722058,0.0002952838,0.0001808894,0.0003279471,0.003080573],"category_scores_gemma":[0.0006350018,0.00008110581,0.0002241232,0.0001821334,0.0002218179,0.0001775131,0.0002347738,0.0003999035,0.0004674788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007932656,"about_ca_system_score_gemma":0.0001156902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008618529,"about_ca_topic_score_gemma":0.0001178359,"domain_scores_codex":[0.9995676,0.0001038475,0.0000641488,0.0001308559,0.00008579664,0.00004776076],"domain_scores_gemma":[0.9995641,0.000144278,0.00006446055,0.00006972473,0.00007498142,0.0000824257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002178097,0.0006221643,0.01908119,0.0001786924,0.00005127474,0.0008717275,0.0003132466,0.0001812955,0.961287,0.0002890952,0.0002774406,0.01466887],"study_design_scores_gemma":[0.0001513755,0.02646685,0.4398195,0.00003476148,0.0002629161,0.00744457,0.000610337,0.001559166,0.5151781,0.0003129314,0.00812828,0.00003132288],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948447,0.0005856122,0.002664652,0.00006204251,0.00003104007,0.000151999,0.0006182644,0.00002034741,0.001021359],"genre_scores_gemma":[0.9955209,0.0003007835,0.001575587,0.0001408887,0.00002029374,0.000227154,0.001384103,0.00001135059,0.0008189227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003080573,"threshold_uncertainty_score":0.01030558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0530361586296243,"score_gpt":0.2902690085897227,"score_spread":0.2372328499600984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}