{"id":"W4281756014","doi":"10.1002/gcc.23074","title":"<i><scp>EWSR1</scp>::<scp>YY1</scp></i> fusion positive peritoneal epithelioid mesothelioma harbors mesothelioma epigenetic signature: Report of 3 cases in support of an emerging entity","year":2022,"lang":"en","type":"article","venue":"Genes Chromosomes and Cancer","topic":"Occupational and environmental lung diseases","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sinai Health System; University of Alberta","funders":"National Cancer Institute","keywords":"Mesothelioma; Calretinin; Pathology; Epigenetics; Fusion gene; Peritoneal mesothelioma; Biology; Mesothelial Cell; Epithelioid cell; Cancer research; Medicine; Immunohistochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002465555,0.0003012341,0.0005757349,0.0003001624,0.000189375,0.00001245665,0.0001554929,0.00009525824,0.0004974717],"category_scores_gemma":[0.00006391663,0.000281834,0.0001866466,0.0005033494,0.0002305242,0.0001462795,0.0002272,0.0001806015,0.000002164371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001499805,"about_ca_system_score_gemma":0.0002219405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001025245,"about_ca_topic_score_gemma":0.0001265586,"domain_scores_codex":[0.9975628,0.0001183818,0.0006313954,0.0005691311,0.000738912,0.0003793525],"domain_scores_gemma":[0.9988336,0.0001489205,0.0003679813,0.0003485222,0.00007332271,0.0002276589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002897181,0.001706628,0.4533247,0.00088211,0.0003504983,0.003156611,0.002896304,0.001218222,0.5224162,0.00005938396,0.002084173,0.01161549],"study_design_scores_gemma":[0.00201327,0.001691257,0.6445323,0.0001821266,0.0003880578,0.00121466,0.003073015,0.0001984846,0.3276021,0.0001286768,0.01880891,0.0001671346],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9739975,0.02327652,0.000004451476,0.0001388399,0.0002552055,0.0004753221,0.001419257,0.00002586666,0.0004070528],"genre_scores_gemma":[0.9938339,0.003876298,0.0001521752,0.0003811587,0.0001857809,0.0001607863,0.0004379453,0.00005135311,0.0009205893],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1948141,"threshold_uncertainty_score":0.9999634,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01016906130317001,"score_gpt":0.2678812875111991,"score_spread":0.257712226208029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}