{"id":"W4281768665","doi":"10.1093/ecco-jcc/jjac075","title":"Targeted Assessment of Mucosal Immune Gene Expression Predicts Clinical Outcomes in Children with Ulcerative Colitis","year":2022,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa; Hospital for Sick Children","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Medicine; Ulcerative colitis; Immune system; Inflammatory bowel disease; Colitis; Immunology; Gene expression; Gene; Gastroenterology; Internal medicine; Disease; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000515922,0.0004318324,0.0004582921,0.0004714451,0.0001843872,0.0005490656,0.00022134,0.0004127806,0.0008415711],"category_scores_gemma":[0.001322027,0.0002249908,0.000420495,0.0005676342,0.0003072183,0.0002740379,0.0003677976,0.0006275998,0.0001990683],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003394922,"about_ca_system_score_gemma":0.0002237852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001202668,"about_ca_topic_score_gemma":0.001851412,"domain_scores_codex":[0.9996835,0.00007214443,0.00002319474,0.0001181441,0.00005321058,0.00004968539],"domain_scores_gemma":[0.9991027,0.0002357372,0.0004594193,0.00005224935,0.00006071595,0.00008917247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002851307,0.00001748102,0.991876,0.0000352638,0.00004124015,0.00008576049,0.00004596631,0.0003759781,0.003227271,0.00001344818,0.0001022268,0.003894215],"study_design_scores_gemma":[0.000008760375,0.0001811552,0.9966709,0.00001786421,0.00005080417,0.0005156972,0.00009745973,0.0009334054,0.001182296,0.00003274491,0.0003045737,0.000004455421],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982504,0.0006109664,0.0004005747,0.00004426423,0.00000394064,0.000007862501,0.0005159175,0.00001193696,0.0001541539],"genre_scores_gemma":[0.9979626,0.0002768831,0.0009747065,0.00003377794,0.000007491416,0.00001545187,0.000627301,0.000006012522,0.00009580603],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001202668,"threshold_uncertainty_score":0.002815306,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007383017463001445,"score_gpt":0.281026595099636,"score_spread":0.2736435776366345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}