{"id":"W4281771147","doi":"10.1200/jco.2022.40.16_suppl.7504","title":"Brentuximab vedotin and association with event-free survival (EFS) in children with newly diagnosed high-risk Hodgkin lymphoma (HL): A report from the Children's Oncology Group phase 3 study AHOD1331 (NCT 02166463).","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; Princess Margaret Cancer Centre; University Health Network","funders":"National Institutes of Health","keywords":"Medicine; Brentuximab vedotin; Internal medicine; Vincristine; Etoposide; Hazard ratio; Regimen; Prednisone; Gastroenterology; Oncology; Surgery; Lymphoma; Cyclophosphamide; Chemotherapy; CD30; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001557878,0.0002365701,0.0004122329,0.0001850316,0.0001472664,0.0003906862,0.0002416271,0.0003632163,0.0009547162],"category_scores_gemma":[0.001683008,0.0001466438,0.0004812697,0.0002518314,0.000259219,0.0002784769,0.0002045914,0.0007165457,0.0001106466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003500252,"about_ca_system_score_gemma":0.0004179546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006891129,"about_ca_topic_score_gemma":0.001433371,"domain_scores_codex":[0.9995278,0.0002633329,0.00003175691,0.00005896263,0.00006399875,0.00005414664],"domain_scores_gemma":[0.9982516,0.0005764689,0.0007178601,0.00008211102,0.00006441766,0.0003075417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.1425966,0.00324264,0.7965562,0.0003307343,0.001322119,0.0002777262,0.0002185034,0.001092881,0.003495943,0.00009444229,0.002070934,0.04870132],"study_design_scores_gemma":[0.01521428,0.04331555,0.9353102,0.00006120782,0.0008338585,0.0007708556,0.00008322985,0.000782166,0.00113097,0.00009199237,0.00238841,0.00001737153],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975435,0.001633745,0.00006989137,0.00008529674,0.0000087587,0.00004243915,0.0003919603,0.000006849978,0.0002175063],"genre_scores_gemma":[0.9985024,0.0003873253,0.0001492869,0.000096768,0.00002050219,0.00005563303,0.0006430444,0.000002928171,0.0001421479],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001557878,"threshold_uncertainty_score":0.008238912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0271985694545777,"score_gpt":0.3686384713430848,"score_spread":0.341439901888507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}