{"id":"W4281802374","doi":"10.1242/jeb.244162","title":"Acute thermal stress elicits interactions between gene expression and alternative splicing in a fish of conservation concern","year":2022,"lang":"en","type":"article","venue":"Journal of Experimental Biology","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Windsor; University of Manitoba","funders":"Fisheries and Oceans Canada; Natural Sciences and Engineering Research Council of Canada; Western Canada Research Grid; Compute Canada; Genome Canada","keywords":"Alternative splicing; Transcriptome; Biology; Gene expression; RNA splicing; Gene; Regulation of gene expression; Cellular stress response; Genetics; Context (archaeology); Cell biology; Messenger RNA; Fight-or-flight response; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001155839,0.0001664306,0.0002566073,0.0002442151,0.0003234942,0.0002153396,0.0001066058,0.0002314747,0.00112227],"category_scores_gemma":[0.0001648556,0.0001795055,0.0003346542,0.0002093275,0.0003305054,0.0001453587,0.0003112873,0.0002985194,0.0001372559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003550403,"about_ca_system_score_gemma":0.0002363874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002962806,"about_ca_topic_score_gemma":0.006078528,"domain_scores_codex":[0.9998693,0.0000126761,0.000009530519,0.00005258313,0.00002376479,0.00003207871],"domain_scores_gemma":[0.9998927,0.00002188627,0.00003371949,0.000009331197,0.0000187215,0.00002363662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00022227,0.00002288116,0.009390729,0.00003388166,0.00001247189,0.00007479398,0.0001194245,0.00004635307,0.9890487,0.00002488492,0.00003502432,0.0009685939],"study_design_scores_gemma":[0.00001737741,0.0009728181,0.8702524,0.0000129146,0.00005874634,0.0003819836,0.0009017368,0.001130704,0.1249935,0.0001553268,0.001092237,0.00003026368],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992884,0.00008976502,0.0002184251,0.00003271642,0.000004871802,0.000005681695,0.0001511379,0.000005474324,0.0002035954],"genre_scores_gemma":[0.9971913,0.0001137683,0.0009167222,0.0001102116,0.00000637675,0.00003602649,0.0004805195,0.000008381905,0.001136661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002962806,"threshold_uncertainty_score":0.005891085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03709703950387882,"score_gpt":0.3108789120798423,"score_spread":0.2737818725759635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}