{"id":"W4281836193","doi":"10.1007/s00441-022-03644-7","title":"Non-human primates in prion diseases","year":2022,"lang":"en","type":"review","venue":"Cell and Tissue Research","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Health Canada; Fifth Framework Programme; Agence Nationale de la Recherche","keywords":"Neuroscience; Human health; Transmissibility (structural dynamics); Biology; Prion Proteins; Pathogenesis; Prion protein; Disease; Virology; Medicine; Immunology; Pathology; Environmental health","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008255191,0.001402258,0.001977485,0.002800674,0.0004387213,0.001204317,0.00110003,0.001937133,0.004138894],"category_scores_gemma":[0.0007386021,0.0003739279,0.0004321346,0.003086975,0.001261964,0.001869071,0.001021031,0.002456953,0.002525636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007264924,"about_ca_system_score_gemma":0.001172519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001611171,"about_ca_topic_score_gemma":0.003149322,"domain_scores_codex":[0.9998373,0.00004096895,0.00002297039,0.00002802194,0.00005434294,0.00001632834],"domain_scores_gemma":[0.9996811,0.000193967,0.00003633066,0.00001323457,0.00004617267,0.00002923466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001188777,0.00006351373,0.0001226543,0.01234492,0.00007142124,0.0004069654,0.00007104462,0.0003308785,0.001554727,0.008218336,0.0537969,0.9228998],"study_design_scores_gemma":[0.0000194085,0.00004536455,0.0003561523,0.0026362,0.00007713672,0.001328931,0.00003622552,0.00004725546,0.000237179,0.004373875,0.9908295,0.0000128803],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003409775,0.998834,0.00009252964,0.0001553365,0.0002267555,0.000002529201,0.00001088609,0.000003996905,0.0006399947],"genre_scores_gemma":[0.000316845,0.9984092,0.000162072,0.0002125933,0.0003470966,0.000006800547,0.00002200005,0.000001356918,0.0005220589],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004138894,"threshold_uncertainty_score":0.01384598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0754077237117074,"score_gpt":0.4420984623494315,"score_spread":0.3666907386377241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}