{"id":"W4281836193","doi":"10.1007/s00441-022-03644-7","title":"Non-human primates in prion diseases","year":2022,"lang":"en","type":"review","venue":"Cell and Tissue Research","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Health Canada; Fifth Framework Programme; Agence Nationale de la Recherche","keywords":"Neuroscience; Human health; Transmissibility (structural dynamics); Biology; Prion Proteins; Pathogenesis; Prion protein; Disease; Virology; Medicine; Immunology; Pathology; Environmental health","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004886695,0.0002135222,0.0004545499,0.0002032691,0.0002492217,0.00007218649,0.0003443713,0.0001815927,0.0003707085],"category_scores_gemma":[0.00005511827,0.0001919809,0.0001196907,0.0002392763,0.0000938766,0.000002970427,0.0007933753,0.0003817739,0.00002163753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004397181,"about_ca_system_score_gemma":0.0002434311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005206047,"about_ca_topic_score_gemma":0.000006904548,"domain_scores_codex":[0.9982156,0.0002844705,0.0002545092,0.0005584051,0.0002732892,0.00041376],"domain_scores_gemma":[0.9992973,0.00005425447,0.00006498677,0.0003839758,0.00002697656,0.0001724914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000009884646,0.00009725612,0.00008242688,0.009192617,0.00001745802,0.00004254851,0.00001150222,2.945658e-7,0.000748032,0.00001726668,0.001084672,0.988696],"study_design_scores_gemma":[0.0001595155,0.0001860925,0.00003164559,0.0006182051,0.00003646193,0.000005949547,0.00001962433,0.000001006013,0.0003153435,0.00006470403,0.9983457,0.000215764],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001146605,0.9971538,0.00000136534,0.000008826779,0.00003757588,0.0007826242,0.00005336033,0.000005985481,0.0008098814],"genre_scores_gemma":[0.0009710335,0.9961507,0.00001514078,0.000005591483,0.0001877758,0.00034096,0.0007178223,0.00004404205,0.001566886],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.997261,"threshold_uncertainty_score":0.7828752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0754077237117074,"score_gpt":0.4420984623494315,"score_spread":0.3666907386377241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}