{"id":"W4281911921","doi":"10.1089/scd.2021.0330","title":"Using Live Imaging and Fluorescence Ubiquitinated Cell Cycle Indicator Embryonic Stem Cells to Distinguish G1 Cell Cycle Delays for General Stressors like Perfluoro-Octanoic Acid and Hyperosmotic Sorbitol or G2 Cell Cycle Delay for Mutagenic Stressors like Benzo(a)pyrene","year":2022,"lang":"en","type":"article","venue":"Stem Cells and Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"National Institute of Environmental Health Sciences; National Institutes of Health","keywords":"Cell cycle; Biology; Cell cycle checkpoint; Cell biology; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003972084,0.0008821826,0.0004163022,0.0007309521,0.0005747648,0.0005045677,0.000557887,0.0008805412,0.003270661],"category_scores_gemma":[0.0001815705,0.0003262491,0.0005251329,0.0006668021,0.0004387957,0.0005252293,0.0004776022,0.001321933,0.001152875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006131493,"about_ca_system_score_gemma":0.0004210953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009978694,"about_ca_topic_score_gemma":0.002407575,"domain_scores_codex":[0.9995067,0.00004171668,0.00004096978,0.0002286055,0.0001251605,0.00005686474],"domain_scores_gemma":[0.9997976,0.00003865079,0.00004788031,0.00003094644,0.00005508436,0.00002984543],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003589314,0.00002193624,0.0002298345,0.00009184148,0.000005373109,0.00004158371,0.00003349385,0.00006928712,0.9964539,0.00019607,0.0001592971,0.002661505],"study_design_scores_gemma":[0.000009025669,0.0001164448,0.002661571,0.00001286107,0.00001535628,0.000183913,0.00003429571,0.00215776,0.9904147,0.0001167497,0.004265248,0.00001207519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5920078,0.003620719,0.3809866,0.000620296,0.0004524002,0.0003865802,0.003874762,0.003638679,0.01441215],"genre_scores_gemma":[0.5240223,0.005547892,0.435444,0.0007670085,0.00009239003,0.001836268,0.005933824,0.0007529684,0.02560333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003270661,"threshold_uncertainty_score":0.01094145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01626379345585834,"score_gpt":0.2506478673128003,"score_spread":0.2343840738569419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}