{"id":"W4281912306","doi":"10.1200/jco.2022.40.16_suppl.7005","title":"Overall survival by <i>IDH2</i> mutant allele (R140 or R172) in patients with late-stage mutant-<i>IDH2</i> relapsed or refractory acute myeloid leukemia treated with enasidenib or conventional care regimens in the phase 3 IDHENTIFY trial.","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"IDH2; Medicine; Internal medicine; Myeloid leukemia; Clinical endpoint; Refractory (planetary science); Gastroenterology; Oncology; Randomized controlled trial; IDH1; Mutant; Gene; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001129625,0.0005029305,0.0008373767,0.000169181,0.0001685388,0.0006710707,0.0003769744,0.0004843788,0.002367137],"category_scores_gemma":[0.0006369575,0.0001821294,0.001070265,0.0002504491,0.0004870721,0.0004646447,0.0004574266,0.002007641,0.0002773056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007392308,"about_ca_system_score_gemma":0.0008591473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006662828,"about_ca_topic_score_gemma":0.002787936,"domain_scores_codex":[0.9997625,0.00009972283,0.00001166784,0.00005330388,0.00002044967,0.00005237938],"domain_scores_gemma":[0.9996315,0.00007091719,0.00008371659,0.00002906486,0.00001753303,0.0001672137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.85562,0.008500133,0.0429455,0.0008982212,0.002296435,0.0001661339,0.000244291,0.003316436,0.009785189,0.0006041366,0.008716721,0.06690677],"study_design_scores_gemma":[0.5813152,0.2835912,0.1115346,0.0002319126,0.004039516,0.0006954701,0.0002254233,0.003798027,0.003998208,0.001437568,0.009055838,0.00007688127],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950922,0.00133623,0.0001359171,0.0002441311,0.00008566841,0.000351943,0.001226293,0.00002254152,0.001505248],"genre_scores_gemma":[0.9941801,0.0007142677,0.0002802613,0.0004337308,0.0000919005,0.0004868514,0.002917262,0.000007004765,0.0008886637],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002367137,"threshold_uncertainty_score":0.007918894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07142988887852038,"score_gpt":0.4136009994397066,"score_spread":0.3421711105611862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}