{"id":"W4281934052","doi":"10.1002/pros.24356","title":"Androgen receptor genomic alterations and treatment resistance in metastatic prostate cancer","year":2022,"lang":"en","type":"review","venue":"The Prostate","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Prostate Cancer Foundation","keywords":"Prostate cancer; Androgen receptor; Medicine; Prostate; Oncology; Prostate disease; Androgen; Internal medicine; Cancer; Receptor; Cancer research; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005294699,0.0005577597,0.001017878,0.001756772,0.0001619068,0.0007833327,0.0006038377,0.0008377028,0.003540982],"category_scores_gemma":[0.0009292517,0.000178545,0.0005363449,0.001746385,0.0003111066,0.000680187,0.0004909096,0.001143671,0.001227177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005509108,"about_ca_system_score_gemma":0.00113487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001356723,"about_ca_topic_score_gemma":0.002191016,"domain_scores_codex":[0.9998385,0.00003703189,0.000022277,0.00002710226,0.00006058551,0.00001457195],"domain_scores_gemma":[0.9996572,0.0001847945,0.00005169511,0.000008066711,0.00007841932,0.00001991031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008053279,0.00003979559,0.0002705955,0.02344991,0.0001678684,0.0001293409,0.00003874156,0.0003568982,0.0006292123,0.003154266,0.02511548,0.9465674],"study_design_scores_gemma":[0.00002433577,0.0001055886,0.001875331,0.0128602,0.0003264428,0.001755033,0.00006321109,0.0001382514,0.000320215,0.002531704,0.979978,0.0000216545],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006181542,0.999084,0.00004357483,0.0001978633,0.0000872951,0.000002146514,0.00001363382,0.000003319862,0.0005063757],"genre_scores_gemma":[0.0005839646,0.9988752,0.00007088612,0.0001373855,0.0000803294,0.000003208124,0.00002247151,7.369985e-7,0.0002257434],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003540982,"threshold_uncertainty_score":0.01184583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09868511844137028,"score_gpt":0.3896992534177602,"score_spread":0.2910141349763899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}