{"id":"W4281955678","doi":"10.1177/10915818221101788","title":"Repeated-Dose Toxicity, Biodistribution, and Shedding Assessments With a ChAd155 Respiratory Syncytial Virus Vaccine Candidate Evaluated in Rabbits and Rats","year":2022,"lang":"en","type":"article","venue":"International Journal of Toxicology","topic":"Respiratory viral infections research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nuclear Laboratories","funders":"GlaxoSmithKline Biologicals","keywords":"Medicine; Viral shedding; Virology; Virus; Respiratory system; Immunology; Immune system; Toxicity; Intramuscular injection; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006519821,0.0005660793,0.0004265834,0.0003759565,0.0001903705,0.0002911787,0.000293842,0.0004820197,0.0004872871],"category_scores_gemma":[0.0003394173,0.000186057,0.0005165514,0.0002084249,0.0003670556,0.0003037763,0.0001626488,0.0006895265,0.0002453154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002658939,"about_ca_system_score_gemma":0.0002927372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001519118,"about_ca_topic_score_gemma":0.001452919,"domain_scores_codex":[0.9997277,0.00007249717,0.00002716369,0.00005094066,0.0000696777,0.00005199894],"domain_scores_gemma":[0.9996494,0.00005590011,0.0001157758,0.00005134498,0.00007999016,0.00004758585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000432398,0.0002622654,0.000443743,0.00004789541,0.00001199303,0.00006526628,0.00006024148,0.0002260751,0.996786,0.0000319612,0.00002640751,0.001605732],"study_design_scores_gemma":[0.00004092804,0.01706917,0.003842606,0.000007814406,0.00006569439,0.000250495,0.0000645785,0.000885525,0.9769356,0.00003627013,0.0007876827,0.00001368877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960153,0.0007245051,0.002320636,0.00003541694,0.00001982633,0.00008791185,0.0001846734,0.00003323378,0.0005785308],"genre_scores_gemma":[0.9927064,0.001437165,0.002642748,0.00003755737,0.00001530309,0.0001158309,0.000392172,0.0000174873,0.002635427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001519118,"threshold_uncertainty_score":0.003448069,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03961171167602648,"score_gpt":0.4034917522324283,"score_spread":0.3638800405564018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}