{"id":"W4281957192","doi":"10.1101/2022.06.07.494954","title":"Altered tRNA processing is linked to a distinct and unusual La protein in <i>Tetrahymena thermophila</i>","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genomics and Phylogenetic Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; York University","funders":"Institute of Genetics; Canadian Institutes of Health Research","keywords":"Tetrahymena; Biology; Transfer RNA; Schizosaccharomyces; Genetics; RNA; Cell biology; Yeast; Saccharomyces cerevisiae; Schizosaccharomyces pombe; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006345353,0.000248614,0.0002429665,0.0002116348,0.0001864603,0.0003341311,0.0001595538,0.0003924713,0.0006698865],"category_scores_gemma":[0.0001299065,0.0001583044,0.0002751526,0.000193161,0.0002247159,0.0001645685,0.0002554919,0.0003871861,0.0003584888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002694124,"about_ca_system_score_gemma":0.0001105892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007169413,"about_ca_topic_score_gemma":0.0005994667,"domain_scores_codex":[0.9999341,0.000007564907,0.000006502366,0.00002362419,0.00001485773,0.00001333093],"domain_scores_gemma":[0.9998397,0.0000145281,0.00008077866,0.00002119243,0.00001170885,0.00003209628],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003942504,0.000003266315,0.0003077733,0.0000102247,0.000002153373,0.00006546095,0.00001383113,0.00001981979,0.9993196,0.00002274243,0.00001425747,0.0001815197],"study_design_scores_gemma":[0.00001359182,0.000205544,0.1008393,0.00001057398,0.00003116739,0.0009219344,0.0001150219,0.001420146,0.8938832,0.0001280229,0.002411855,0.00001968423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981109,0.0002176088,0.000928292,0.00004629343,0.000008925287,0.000004499092,0.0004000971,0.0000633317,0.0002200685],"genre_scores_gemma":[0.9971675,0.0001008087,0.0009251426,0.00004429374,0.000006880296,0.00001090567,0.0009644841,0.00003365736,0.0007462778],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007169413,"threshold_uncertainty_score":0.002241015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01139959768332746,"score_gpt":0.2257126570184857,"score_spread":0.2143130593351582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}